. Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease. Mitochondrion. 2007 Sep;7(5):297-310. PubMed.

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  1. A very interesting review on mitochondrial dysfunction and energy hypometabolism in AD, highlighting the interaction of cellular heme and Aβ. From our own proteomics and functional studies we have evidence for a mitochondrial dysfunction in tauopathies (David et al., 2005).

    References:

    . Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem. 2005 Jun 24;280(25):23802-14. PubMed.

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