David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Müller WE, Eckert A, Götz J. Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem. 2005 Jun 24;280(25):23802-14. PubMed.

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- John Trojanowski
  University of Pennsylvania
- Posted: 27 Apr 2005
The study extends insights into the consequences of tau pathology that involve a mitochondrial and oxidative stress.

View all comments by John Trojanowski

- Nikolaos K. Robakis
  Mount Sinai School of Medicine, NYU
- Posted: 27 Apr 2005
An interesting paper, suggesting involvement of mitochondria in fronto-temporal dementia.

View all comments by Nikolaos K. Robakis

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