Postdoctoral Fellow


University of Pittsburgh


Pittsburgh, Pennsylvania

Principal Investigator

Radosveta Koldamova and Iliya Lefterov

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Two postdoctoral fellow positions are available in the Iliya Lefterov and Radosveta Koldamova laboratory in the Department of Environmental and Occupational Health The successful candidates will become part of a large, multidisciplinary neuroscience and environmental health community, and will have ample opportunities for collaborations. Positions are supported by NIH grants with goals of understanding the role of Apolipoprotein E in the risk and pathogenesis of Alzheimer's Disease and how transcription factors and other regulators of lipid homeostasis impact the outcomes of neurodegeneration, especially Alzheimer’s disease. These projects require integration of multiple techniques for rodent behavioral analysis, brain surgery, histological, molecular, and genetic analysis of pathological markers.


Both candidates should have an M.D./Ph.D. in neuroscience, cell biology/physiology, or biochemistry/molecular biology/molecular genetics, with a track record of productivity.

1) For the first position, solid background and hands-on experience with transgenic mouse colony maintenance, small animal rodent surgery, experience with immunohistochemistry using confocal microscope as well as behavioral testing to study the nervous system are required.

2) For the second position, knowledge and experience in molecular biology and biochemistry with an emphasis on lipid metabolism and its regulation are requirements. Previous work with methods relevant to transcriptomics, lipidomics and proteomics, as well as analysis of NGS data are desirable.

Experience with bioinformatics tools, R-statistics, Unix/Mac OS platforms will be considered a plus.

The candidates should have creative thinking, excellent communication skills, and ability to work collaboratively. Applications should include curriculum vitae and names/contact information of three professional references.