Postdoctoral Research Scientist


Washington University School of Medicine


St. Louis, Missouri

Principal Investigator

Carlos Cruchaga



The NeuroGenomics and Informatics Center  (NGI) at Washington University School of Medicine is recruiting multiple postdoctoral research scientists. The NGI generates and analyzes whole-genome sequencing data and high-throughput, multi-dimensional omic data to study neurodegeneration and diseases of the central nervous system, with an emphasis on Alzheimer's disease, Parkinson’s disease, and other dementias. The ultimate goal of the NGI is to understand the biology of these diseases, to define novel biomarkers, and to identify novel therapeutic targets. The Washington University School of Medicine is renowned for its research cohorts of neurodegenerative disorders, which include clinical, neuroimaging, and fluid biomarker phenotypes.

WUSLU has recently received several NIH R01 awards to generate and analyze large WGS datasets for both familial Alzheimer disease and sporadic early onset cases. It is seeking highly motivated researchers with strong analytical skills, especially in genetics and WGS/WES analyses, to lead the analyses for these projects. The new postdoc(s) will join a large team, currently 20 members, which is led by three faculty members, four postdocs, several Ph.D. students, and three senior scientists.

For further details please see

Pre-Employment Screening: All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment, and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits: This position is eligible for full-time benefits.  Please click the following link to view a summary:

EOE Statement: Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.


A successful applicant will have:

  • A Ph.D. in genetics, bioinformatics, computer science, data science, statistical genomics, or a related discipline involving the interrogation of omics datasets, or expect to obtain a degree in the near future.
  • Hands-on experience using PLINK, SKAT, BWA, and/or GATK with large-scale human genomic or other omics (preferably related to neurodegeneration) studies.
  • Solid skills in at least one programming language (R, python, or perl) and experience working in Linux and/or high-performance cluster environments.
  • A strong ability to perform analytical reasoning to extract biological insights from data-driven approaches.
  • Familiarity with interrogation of publicly available resources (highly beneficial).