Jobs

Postdoctoral Fellow

Employer

University of North Carolina at Charlotte

Location

Charlotte , North Carolina

Principal Investigator

Kristen Funk

Contact

kfunk@uncc.edu

Description

To see full description, requirements and apply please visit: https://jobs.uncc.edu/postings/28180

The successful candidate will join the laboratory of Kristen Funk in an NIH-funded research project to understand the impact of neuroinflammatory events, particularly viral encephalitis, on the development of Alzheimer’s disease pathology and cognitive dysfunction. The postdoctoral researcher will conduct independent research, remain abreast of developments in the fields of neuroimmunology, neurovirology, and Alzheimer’s disease, and develop novel research tools and methods as needed. He or she will also work directly with the research team to conduct the proposed studies, analyze and interpret data, perform all the other related research activities and duties as required, work with collaborators to develop proposals for research funding, present the findings in international conferences/symposia, and publish research articles in a timely manner.

Project Outline: Alzheimer’s disease is estimated to affect 5.3 million Americans currently and is expected to rise over the next decade. Neuroinflammation is increasingly recognized as contributing to disorders of the central nervous system including AD. The goal of this project is to test the hypothesis that viral encephalitis may enhance inflammatory events that accelerate the normal processes of CNS aging and contribute to the development of AD pathology. The successful applicant will work with murine and cell culture models, including immortalized cell lines and primary cell culture models. The studies will employ a broad spectrum of molecular biology, cell/tissue culture, cell imaging, flow cytometry, transcriptomics, including mice handling and surgical techniques.

Requirements

  • Ph.D. in neurobiology, immunology, virology, molecular biology, cell biology, genetics, or related fields, with a proven record of peer-reviewed first-author publications in the related field of research.
  • Proficiency with routine molecular and cellular biology techniques, immunology skills, sterile cell culture, DNA, RNA, and protein-based assays including animal handling experience.