Jobs
Research Fellow in Molecular Neuropathology
Posted 28 Apr 2024
Employer
Indiana University School of Medicine
Principal Investigator
Description
The Dementia Laboratory, co-led by Bernardino Ghetti and Kathy L. Newell of the Indiana University School of Medicine Department of Pathology and Laboratory Medicine Division of Neuropathology, has immediate full-time openings for one or more outstanding, highly motivated postdoctoral research fellows with special interest in molecular pathology of neurodegeneration related to aging as well as sporadic and genetically-determined dementias and motor neuron diseases. These include Alzheimer’s disease, frontotemporal dementias, Parkinson’s disease, amyotrophic lateral sclerosis, and prion diseases. The faculty of the laboratory are well-funded.
This is a three-year fellowship that provides the opportunity to develop and expand knowledge in the neuropathology of human neurodegenerative diseases using light microscopy, immunohistochemistry, electron microscopy, immunoelectron microscopy, fluorescent multiplex immunohistochemistry, digital spatial profiling, quantitative digital image analysis, and cryo electron microscopy. Additionally, fellows have the opportunity to participate in and develop multidisciplinary projects integrating neuropathology with cutting-edge brain imaging, clinical neurology, protein chemistry, and molecular genetics as well as communicate and collaborate with leading researchers from around the world. Fellows may focus on one or more misfolded proteins and acquire an understanding of co-pathologies of amyloids simultaneously involving a single anatomical system.
The laboratory’s focus is on the molecular neuropathology of neurodegenerative diseases. Its aims are to expand our knowledge of the mechanisms of neurodegeneration. Its personnel consists of faculty, staff and students focused on expanding the knowledge on neurodegeneration and the associated misfoled proteins. It provides an environment for a multidisciplinary approach to the study of neurodegenerative dementias. The laboratory’s Brain Library contains specimens from well over 2500 individuals collected over the past 45 years, offering a unique opportunity to study a wide range of neurodegenerative diseases occurring in a variety of ages, sexes, and racial and ethnic groups.
Requirements
- Must have a Ph.D., M.D., or M.D./Ph.D. with strong training in human neuroanatomy or neuropathology.
- Must have experience in light microscopy and neurohistology.
- Must have good written and oral communication skills.
- Must have evidence of manuscript writing and publication.