PAPER He W, Shi X, Dong Z

The roles of RACK1 in the pathogenesis of Alzheimer's disease.

J Biomed Res. 2024 Feb 27;38(2):137-148. PubMed: 38410996

PAPER Sakowski SA, Koubek EJ, Chen KS, Goutman SA, Feldman EL

Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions.

Ann Neurol. 2024 Apr;95(4):635-652. Epub 2024 Feb 27 PubMed: 38411261

PAPER Shim KH, Kim D, Kang MJ, Pyun JM, Park YH, Youn YC, Park KW, Suk K, Lee HW, Gomes BF, Zetterberg H, An SS, Kim S, Alzheimer's Disease All Markers (ADAM) Research group

Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease.

Alzheimers Dement. 2024 Apr;20(4):2731-2741. Epub 2024 Feb 27 PubMed: 38411315

PAPER Syvänen V, Koistinaho J, Lehtonen Š

Identification of the abnormalities in astrocytic functions as potential drug targets for neurodegenerative disease.

Expert Opin Drug Discov. 2024 May;19(5):603-616. Epub 2024 Feb 26 PubMed: 38409817

PAPER Golan Shekhtman S, Boccara E, Ravona-Springer R, Inbar Y, Zelicha H, Livny A, Bendlin BB, Lesman-Segev O, Yore I, Heymann A, Sano M, Mardor Y, Azuri J, Schnaider Beeri M

Abdominal fat depots are related to lower cognitive functioning and brain volumes in middle-aged males at high Alzheimer's risk.

Obesity (Silver Spring). 2024 May;32(5):1009-1022. Epub 2024 Feb 27 PubMed: 38410053

PAPER Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR

Author Correction: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology.

Nat Chem Biol. 2024 May;20(5):656. PubMed: 38413747

PAPER Brokate-Llanos AM, Sanchez-Ibañez M, Pérez-Jiménez MM, Monje-Moreno JM, Gómez-Marín C, Caro C, Vivar-Rios C, Moreno-Mateos MA, García-Martín ML, Muñoz MJ, Royo JL

Ribonucleotide reductase inhibition improves the symptoms of a Caenorhabditis elegans model of Alzheimer's disease.

G3 (Bethesda). 2024 May 7;14(5) PubMed: 38412549

Hyouna Yoo

Haylee Mesa

Postdoctoral Scholar

JOB 2024-02-27 Employer University of California, San Diego Principal Investigator Jeremy Elman Contact To apply: Please submit a cover letter, CV, and letters from three references to Drs. Jeremy Elman (jaelman@health.ucsd.edu) and Matthew Panizzon (mspanizzon@health.u

Jeanne Lenzer

Kingston, United States

Debomoy Lahiri, Bryan Maloney on Epigenetic Shenanigans—In AD, Chromatin Opens Up in Blood Immune Cells

COMMENT We read the this paper (Ramakrishnan et al., 2024) with great interest and agree with others’ comments already posted in Alzforum. We have long maintained that there is an important role for epigenetic markers in the etiology of AD (Maloney and Lahiri, 20

PAPER Galea I, Bechmann I, Perry VH

What is immune privilege (not)?

Trends Immunol. 2007 Jan;28(1):12-8. Epub 2006 Nov 28 PubMed: 17129764

Chiara Cirelli on While a Fly Sleeps, Its Glia Burn Neuronal Lipids to Refresh the Brain

COMMENT This is a beautiful study with compelling results. That the authors discovered a role for glia in protecting neurons from wake-related oxidative stress is quite unexpected and eye-opening. The next step will be to test the extent to which this mechanism a