Hanjun Lee

Massachusetts Institute of Technology
Cambridge, United States

Odetta Antico

Dundee, United Kingdom

Non-Invasive Neurostimulation in AD/ADRD (R01 Clinical Trial Optional) (PAR-19-298)

GRANT Friday, June 14, 2019- 17:45 National Institute on Aging, National Institute of Mental Health Standard dates apply, by 5 p.m. local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are ...

Characterization of Marmosets as Models of Aging and Age-Related Diseases (U34 Clinical Trial Not Allowed) (RFA-AG-20-007)

GRANT Friday, June 14, 2019- 17:45 National Institute on Aging NIA intends to commit $787,500 in FY 2020 to fund two awards. October 22, 2019, by 5 p.m. local time of applicant organization. Characterization of Marmosets as Models of Aging and Age-Related ...

Aging, Driving and Early Detection of Dementia (R01 Clinical Trial Optional) (RFA-AG-20-022)

GRANT Friday, June 14, 2019- 17:45 National Institute on Aging NIA intends to commit $3 million in FY 2020 to fund four to six awards. October 22, 2019, by 5 p.m. local time of applicant organization. Aging, Driving and Early Detection of Dementia (R01 Clinical ...

Mechanistic Basis of Diffuse White Matter Disease in Vascular Contributions to Cognitive Impairment and Dementia (VCID) (R01 Clinical Trial Not Allowed) (RFA-NS-19-039)

GRANT Friday, June 14, 2019- 17:45 National Institute of Neurological Disorders and Stroke, National Institute on Aging NINDS intends to commit up to $3.75 million in FY 2020 to fund up to six awards. August 14, 2019, by 5 p.m. local time of applicant ...

Bernard Hanseeuw on Parsing Local and Distal Aβ Shows Links to Metabolism, Cognition

COMMENT I really liked how the authors used the regional data to ask whether amyloid had a local, global, or distant effect. The data convincingly confirm the absence of local toxicity of fibrillar Aβ, as detected using PET. It also shows that Aβ burden globally ...

Postdoctoral Research Fellowship

JOB 2019-06-14 Employer Tufts University School of Medicine Principal Investigator Giuseppina Tesco Contact E-mail your curriculum vitae, reprints, statement of interest and career goals, and names, email addresses and telephone numbers of at least three references to: ...

Bernard Hanseeuw

Cliniques Universitaires Saint-Luc and Massachusetts General Hospital
Brussels, Belgium

Parsing Local and Distal Aβ Shows Links to Metabolism, Cognition

RESEARCH NEWS 2019-06-14 Research News For decades, researchers have wondered why Aβ deposits in the brain correlate poorly with local neural activity and cognition. Perhaps the correlation was not that weak, after all. A study in the June 4 Nature Communications suggests that it ...

David Jones on Parsing Local and Distal Aβ Shows Links to Metabolism, Cognition

COMMENT This is an interesting study that is trying to address an important apparent spatiotemporal paradox that arises when researchers try to reconcile large-scale spatial and temporal patterns associated with AD physiology and small-scale molecular events ...

PAPER van den Heuvel MP, Sporns O

A cross-disorder connectome landscape of brain dysconnectivity.

Nat Rev Neurosci. 2019 May 24; PubMed: 31127193

Marcus Raichle on Parsing Local and Distal Aβ Shows Links to Metabolism, Cognition

COMMENT This is a very interesting paper. One of the intriguing features of AD is the anatomy of the human brain that is vulnerable. I believe that a reasonable consensus is that it involves the hippocampus and the default mode network, which has been ...

Sliced by ApoE Genotype, Whole Exome Data Yield New AD Variants

RESEARCH NEWS 2019-06-14 Research News Does the head honcho of genetic Alzheimer’s risk occlude contributions of smaller genes? In the June 10 JAMA Neurology, researchers led by Lindsay Farrer at Boston University exposed some hidden variants that have languished in the shadow of ...

PAPER Mitter D, Pringsheim M, Kaulisch M, Plümacher KS, Schröder S, Warthemann R, Abou Jamra R, Baethmann M, Bast T, Büttel HM, Cohen JS, Conover E, Courage C, Eger A, Fatemi A, Grebe TA, Hauser NS, Heinritz W, Helbig KL, Heruth M, Huhle D, Höft K, Karch S, Kluger G, Korenke GC, Lemke JR, Lutz RE, Patzer S, Prehl I, Hoertnagel K, Ramsey K, Rating T, Rieß A, Rohena L, Schimmel M, Westman R, Zech FM, Zoll B, Malzahn D, Zirn B, Brockmann K

FOXG1 syndrome: genotype-phenotype association in 83 patients with FOXG1 variants.

Genet Med. 2018 Jan;20(1):98-108. Epub 2017 Jun 29 PubMed: 28661489