Poul Henning Jensen on Blunt Instruments: α-Synuclein Antibodies Poorly Distinguish Forms

COMMENT The comprehensive comparison of aggregate-selective α-synuclein antibodies by Kumar et al. has been published after the preprint version earlier was published on BioRxiv. The field’s responses are positive—but then what? I think the title of this Alzforum ...

Kasinath Viswanathan

Zydus Research Centre
Ahmedabad, India

Lan Guo

Lawrence

Michael Peppy

APP D332G

MUTATIONS APP 27372368 GRCh37 (105) rs773998162 A G Exon 7 Point, Missense Coding Unknown, but predicted to be damaging by PolyPhen-2 and tolerated by SIFT. Unknown, but MRI showed atrophy of the hippocampus and of the temporal and parietal lobes. D332G Alzheimer& ...

APP T297M

MUTATIONS APP 27372473 GRCh37 (105) rs557227002 C T Exon 7 Point, Missense Coding Unknown, but predicted to be damaging by PolyPhen-2 and deleterious by SIFT. Unknown. T297M Alzheimer's Disease: Unclear PathogenicityAlzheimer's Disease This variant was ...

NYAS- Brain Health: Diet, Exercise, and Disease Prevention

CONFERENCE 2020-12-08 00:00:00-2020-12-08 00:00:00 Online Meeting 08 December 2020 Time: 11:30 am- 1:00 pm EST View Conference Website 0 ...

APP D244G

MUTATIONS APP 27394290 GRCh37 (105) rs1347585131 A G Exon 6 Point, Missense Coding Unknown, but predicted to be probably damaging by PolyPhen-2 and tolerated by SIFT. Unknown. D244G Alzheimer's Disease: Unclear PathogenicityAlzheimer's Disease This ...