Christian Bancher
LK HornAustria
345937 RESULTS
LK HornAustria
COMMENT This is an important study for fluid biomarker development in FTD. The results could support further diagnostic and therapeutic development in FTD, a condition with no cure and for which no specific diagnostic test exist. The study in this European cohort
COMMENT This is a very impactful paper. The authors found distinct and shared proteomic alterations across genetic FTD subtypes. Each genetic FTD mutation (C9ORF72, GRN, MAPT) displayed unique CSF proteomic changes. Some proteins were altered across all three sub
COMMENT This is impressive work. The relatively large number of individuals per genetic subtype included explains the large number of proteins identified. The paper is a very valuable source for other proteomics studies. There are not so many proteomics studies p
RESEARCH NEWS 2025-02-09 Research News Scientists are urgently seeking fluid biomarkers for frontotemporal dementia, the most common dementing illness among 40- and 50-year-olds. Two large collaborations studying genetic FTD cohorts have now cracked open the door. In one, scienti
Xiamen University, China
United States
, Nigeria
Acurex Biosciences Corp.United States
COMMENT The maintenance dose is hugely welcome, but we need FDA approval of the epipen. TAAAFT_407236 0
COMMENT As a practical matter, this is wonderful news for our practice. We currently have about 10 people who will adopt this dose and many to follow. This frees us up to accommodate new doses, help more people, and provides a goal which is sure to help discussio
COMMENT By showing that the maternal X-chromosome (Xm) affects cognition in female mice, this study highlights that sex differences in aging cognition could be partly explained by skewed inactivation of the X-chromosome toward Xm. Next steps would be to assess wh
RESEARCH NEWS 2025-02-07 Research News In Alzheimer’s disease, microglia pack on fat, which impairs phagocytosis. Now, scientists led by Christiane Ruedl of Nanyang Technological University, Singapore, report that blocking lipid buildup in these cells restores their capacity to e
COMMENT This study contributes to a growing body of research on the role of microglial lipid metabolism in Alzheimer’s disease. Important studies from the labs of Tony Wyss-Coray, Li-Huei Tsai, Mathew Blurton-Jones, Gaurav Chopra, Erik Musiek, and many others sho
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