248300 RESULTS
COMMENT Jesse Brown and colleagues combined healthy functional connectome with patient baseline MRI to predict individual patterns of longitudinal gray-matter atrophy in patients with behavioral variant frontotemporal dementia (bvFTD) and semantic variant primary ...
Yale UniversityNew Haven, United States
GRANT Friday, October 18, 2019- 18:00 National Institute of Neurological Disorders and Stroke, National Institute on Alcohol Abuse and Alcoholism February 11, 2020; June 9, 2020; October 14, 2020; February 11, 2021; June 9, 2021; October 14, 2021; February 9, ...
GRANT Friday, October 18, 2019- 18:00 National Institute on Aging NIA intends to commit $1.6 million in total costs in FY 2020 to fund two awards. February 3, 2020 NIA Behavioral and Social Research LEaders in Alzheimers Disease and Its Related Dementias (NIA ...
GRANT Friday, October 18, 2019- 17:45 National Institute on Aging Standard dates apply, by 5 p.m. local time of applicant organization. Aging Research Dissertation Awards to Increase Diversity (R36 Clinical Trial Not Allowed) (PAR-19-394) ...
COMMENT I find the work by Brown et al. to be important and interesting in that they provide a novel framework for single-subject outcome measures based on network physiology. This provides more evidence that the key biology at play in neurodegenerative diseases ...
COMMENT This is very elegant work from Jesse Brown and colleagues. I found two aspects of the study particularly noteworthy. The first is the idea of a personalized prediction model of longitudinal brain atrophy based on the trans-neuronal spreading hypothesis. ...
RESEARCH NEWS 2019-10-18 Research News In neurodegenerative diseases, specific brain regions take the brunt of pathology and atrophy. However, differences from one patient to another make it hard to predict the precise path of progression for any one person. Now, scientists led ...
PAPER Brown JA, Deng J, Neuhaus J, Sible IJ, Sias AC, Lee SE, Kornak J, Marx GA, Karydas AM, Spina S, Grinberg LT, Coppola G, Geschwind DH, Kramer JH, Gorno-Tempini ML, Miller BL, Rosen HJ, Seeley WW
COMMENT Dissecting the contribution of p-tau itself versus the innate immune system to neuronal loss in a model of tau pathology, this new study from the lab of David Holtzman showed that neuronal pathology and loss is almost exclusively driven by microglia. ...
RESEARCH NEWS 2019-10-18 Research News Why do some people age better than others? In the October 16 Nature, researchers led by Bruce Yankner at Harvard Medical School once again credit the repressor element 1-silencing transcription factor (REST). People who lived to a ripe old ...
COMMENT The need to understand drivers of healthy aging is critically important for today’s society, one that invests heavily in promoting longevity but continues to be burdened by age-associated impairments. In their recent paper, Zullo, Drake, and colleagues ...
UC San DiegoLa Jolla, United States
PAPER Tavernarakis N
PAPER Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaiácovo MP, Yankner BA
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