Knafo S, Alonso-Nanclares L, Gonzalez-Soriano J, Merino-Serrais P, Fernaud-Espinosa I, Ferrer I, Defelipe J.
Widespread changes in dendritic spines in a model of Alzheimer's disease.
Cereb Cortex. 2009 Mar;19(3):586-92.
PubMed.
This appears to be a well-done study that, however, leaves open a number of issues: what is the correlation of the observed dendritic spine data to pertinent behavioral measures and to stereological synapse data—all in the same animals.
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Banner Research Institute
This appears to be a well-done study that, however, leaves open a number of issues: what is the correlation of the observed dendritic spine data to pertinent behavioral measures and to stereological synapse data—all in the same animals.
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