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Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, McConlogue L, Masliah E, Mucke L. TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med. 2001 May;7(5):612-8. PubMed.
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Boston University School of Medicine
This is a novel mechanism for reducing Ab plaque load. The interaction between Ab and TGFb has been noted earlier, but this paper sheds important new information on the affects of TGFb on Ab.
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