. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet. 2001 Aug;28(4):345-9. PubMed.


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  1. "This paper provides novel insights into the pathophysiology of a disease that pathologically shares similarities with Parkinson’s disease. The identification of PanK2 therefore has broad implications for neurodegenerative disease."

  2. "This provides a great impact and concept to us. Ferrous accumulation diseases such as PKAN (pantothenate-kinase-associated neurodegeneration) or neuroferritinopathy would strongly show a new view for another general neurodegenerating disorders."

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