Galimberti D, Venturelli E, Fenoglio C, Guidi I, Villa C, Bergamaschini L, Cortini F, Scalabrini D, Baron P, Vergani C, Bresolin N, Scarpini E. Intrathecal levels of IL-6, IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration. J Neurol. 2008 Apr;255(4):539-44. Epub 2008 Jan 23 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(43)		 384.5 ± 119.6
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
Other Controls
(30)		 996.2 ± 261.7
pg/mL		 ELISA;
Innotest;
Innogenetics
Aβ42
(CSF)		 FTD
(24)		 842.2 ± 383.9
pg/mL		 ELISA;
Innotest;
Innogenetics		 Neary et al., 1998
tau-p181
(CSF)		 AD
(43)		 71.3 ± 35
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-p181
(CSF)		 CTRL-
Other Controls
(30)		 27.4 ± 20
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)		 FTD
(24)		 47.4 ± 28.2
pg/mL		 ELISA;
Innotest;
Innogenetics		 Neary et al., 1998
tau-total
(CSF)		 AD
(43)		 681.5 ± 279.5
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 CTRL-
Other Controls
(30)		 160.1 ± 96.2
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 FTD
(24)		 428.2 ± 270.6
pg/mL		 ELISA;
Innotest;
Innogenetics		 Neary et al., 1998

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. CTRL vs AD : Aβ42 (CSF)
  3. FTD vs AD : Aβ42 (CSF)
  4. AD vs CTRL : tau-p181 (CSF)
  5. CTRL vs AD : tau-p181 (CSF)
  6. FTD vs AD : tau-p181 (CSF)
  7. AD vs CTRL : tau-total (CSF)
  8. CTRL vs AD : tau-total (CSF)
  9. FTD vs AD : tau-total (CSF)