Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H, Wiltfang J, Frölich L, Heuser I. Hypocretin in cerebrospinal fluid is positively correlated with Tau and pTau. Neurosci Lett. 2014 Feb 21;561:41-5. Epub 2013 Dec 25 PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ40 (CSF)
- CTRL vs AD : Aβ40 (CSF)
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ40 (CSF) |
AD (10) |
77.7 ± 24.7 pg/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
McKhann et al., 1984 |
| Aβ40 (CSF) |
CTRL- Other Controls (10) |
105.1 ± 37.9 pg/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
1993 |
| Aβ42 (CSF) |
AD (10) |
459 ± 170 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
CTRL- Other Controls (10) |
687 ± 231 pg/mL |
ELISA; Innotest; Innogenetics |
1993 |
| tau-p181 (CSF) |
AD (10) |
76 ± 32 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-p181 (CSF) |
CTRL- Other Controls (10) |
53.9 ± 22.9 pg/mL |
ELISA; Innotest; Innogenetics |
1993 |
| tau-total (CSF) |
AD (10) |
369 ± 111 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- Other Controls (10) |
237 ± 90 pg/mL |
ELISA; Innotest; Innogenetics |
1993 |
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