. Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy. J Neurol Neurosurg Psychiatry. 2015 Mar;86(3):244-50. Epub 2014 Jun 4 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(37)
237.5 ± 82.7
pg/mL
xMAP;
AlzBio3;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(37)
348.1 ± 75.7
pg/mL
xMAP;
AlzBio3;
Innogenetics
Aβ42
(CSF)
PSP
(23)
269 ± 87
pg/mL
xMAP;
AlzBio3;
Innogenetics
Litvan et al., 1996
tau-p181
(CSF)
AD
(37)
44.7 ± 25.7
pg/mL
xMAP;
AlzBio3;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(37)
29.1 ± 9.4
pg/mL
xMAP;
AlzBio3;
Innogenetics
tau-p181
(CSF)
PSP
(23)
22.1 ± 7.4
pg/mL
xMAP;
AlzBio3;
Innogenetics
Litvan et al., 1996
tau-total
(CSF)
AD
(37)
138.4 ± 88.6
pg/mL
xMAP;
AlzBio3;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(37)
79 ± 33.1
pg/mL
xMAP;
AlzBio3;
Innogenetics
tau-total
(CSF)
PSP
(23)
55.9 ± 20.1
pg/mL
xMAP;
AlzBio3;
Innogenetics
Litvan et al., 1996

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