de Almeida SM, Ribeiro CE, Rotta I, Letendre S, Potter M, Tang B, Batistela M, Vaida F, Ellis RJ, HIV Neurobehavioral Research Center (HNRC) Group. Blood amyloid-β protein isoforms are affected by HIV-1 in a subtype-dependent pattern. J Neurovirol. 2019 Jul 7; PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ40 (Plasma and Serum)
- CTRL vs AD : Aβ40 (Plasma and Serum)
- AD vs CTRL : Aβ42 (Plasma and Serum)
- CTRL vs AD : Aβ42 (Plasma and Serum)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ40 (Serum) |
AD (24) |
833 ± 3161 pg/mL § |
Electrochemiluminescence; Other/Not Specified; Meso Scale Discovery |
McKhann et al., 2011 |
Aβ40 (Serum) |
CTRL- CNC (18) |
124.4 ± 70.65 pg/mL § |
Electrochemiluminescence; Other/Not Specified; Meso Scale Discovery |
|
Aβ42 (Serum) |
AD (24) |
86.6 ± 357.1 pg/mL § |
Electrochemiluminescence; Other/Not Specified; Meso Scale Discovery |
McKhann et al., 2011 |
Aβ42 (Serum) |
CTRL- CNC (18) |
8.08 ± 3.45 pg/mL § |
Electrochemiluminescence; Other/Not Specified; Meso Scale Discovery |
§ Data supplied to Alzforum by author
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