Li X, Li TQ, Andreasen N, Wiberg MK, Westman E, Wahlund LO. The association between biomarkers in cerebrospinal fluid and structural changes in the brain in patients with Alzheimer's disease. J Intern Med. 2014 Apr;275(4):418-27. Epub 2013 Dec 11 PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ42 (CSF) |
AD (21) |
483.8 ± 130.8 pg/mL |
ELISA; Innotest; Innogenetics |
1991 |
Aβ42 (CSF) |
CTRL- Other Controls (22) |
1089.2 ± 306 pg/mL |
ELISA; Innotest; Innogenetics |
|
tau-p181 (CSF) |
AD (21) |
88.9 ± 32.9 pg/mL |
ELISA; Innotest; Innogenetics |
1991 |
tau-p181 (CSF) |
CTRL- Other Controls (22) |
51.8 ± 19.8 pg/mL |
ELISA; Innotest; Innogenetics |
|
tau-total (CSF) |
AD (21) |
634.7 ± 275.9 pg/mL |
ELISA; Innotest; Innogenetics |
1991 |
tau-total (CSF) |
CTRL- Other Controls (22) |
277.1 ± 125.3 pg/mL |
ELISA; Innotest; Innogenetics |
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