. The association between biomarkers in cerebrospinal fluid and structural changes in the brain in patients with Alzheimer's disease. J Intern Med. 2014 Apr;275(4):418-27. Epub 2013 Dec 11 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(21)
483.8 ± 130.8
pg/mL
ELISA;
Innotest;
Innogenetics
1991
Aβ42
(CSF)
CTRL-
Other Controls
(22)
1089.2 ± 306
pg/mL
ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)
AD
(21)
88.9 ± 32.9
pg/mL
ELISA;
Innotest;
Innogenetics
1991
tau-p181
(CSF)
CTRL-
Other Controls
(22)
51.8 ± 19.8
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(21)
634.7 ± 275.9
pg/mL
ELISA;
Innotest;
Innogenetics
1991
tau-total
(CSF)
CTRL-
Other Controls
(22)
277.1 ± 125.3
pg/mL
ELISA;
Innotest;
Innogenetics

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