Antibody

Synaptobrevin-2/VAMP-2 (69.1)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Synaptic Systems
Cat# 104211
available fluorescence labelled as 104211C3
References:
Burré J, 2010
Ihara, 2007
Formulation: lyophilized, purified IgG
Reactivity:
Reacts in: Human, Hamster, Mouse, Rat
no signal in chicken

Immunogen/Epitope

immunogen = synthetic peptide (SATAATVP PAAPAGEG) corresponding to residues 2-17 of rat Synaptobrevin 2, coupled to KLH

Specificity

specific for Synaptobrevin2/ VAMP2; no cross with VAMP1 or VAMP3

Note

IC for 1042111C3; ELISA capture

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References

Paper Citations

  1. Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7. PubMed.
  2. Ihara M, Yamasaki N, Hagiwara A, Tanigaki A, Kitano A, Hikawa R, Tomimoto H, Noda M, Takanashi M, Mori H, Hattori N, Miyakawa T, Kinoshita M. Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron. 2007 Feb 15;53(4):519-33. PubMed.

Further Reading

No Available Further Reading