Posted 19 Jul 2018
King's College London
London, England, United Kingdom
To apply, please go to https://www.hirewire.co.uk/HE/1061247/MS_JobDetails.aspx?JobID=79428.
Applications are invited for a postdoctoral research associate in the Department of Basic and Clinical Neuroscience in King’s College London. The post is funded by The Alzheimer’s Society for one year and 11 months.
The project will focus on the role of defective endoplasmic reticulum (ER)-mitochondria signaling in dementia and especially frontotemporal dementia (FTD). It aims to study the mechanisms that control this signaling, including how interactions between ER-mitochondria tethering proteins are regulated. It also aims to determine the potential benefits of using pharmacologically active compounds to correct damaged ER-mitochondria signaling in cell and transgenic models of FTD. Experience in working with transgenic mouse models, advanced microscopy, biochemical, cell, and molecular biology approaches including neurons would be advantageous. Knowledge of defective signaling processes in dementia and related disorders will also be useful.
The successful applicant will join an established research group headed by Professor Chris Miller and Dr. Wendy Noble, see https://www.kcl.ac.uk/ioppn/depts/bcn/Our-research/Neurodegeneration/miller-cell-biology-als/about-us.aspx, and the work will be undertaken in labs that form part of the King’s College UK Dementia Research Institute.
See job description at https://www.hirewire.co.uk/HE/1061247/MS_JobDetails.aspx?JobID=79428.