Antibody

Tau (5E2)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Upstate and Chemicon are Millipore
Cat# 05-348
Catalog #: Cat# 05-348
Formulation: 0.1M Tris-glycine, pH 7.4, containing and 0.05% sodium azide
Reactivity:
Reacts in: Bovine, Human, Rabbit, Mouse, Rat
Availability: Confirmed available January 2015

Immunogen/Epitope

The immunogen consists of fetal, heat-stable, microtubule associated proteins (MAPS).

Specificity

This antibody binds native and phosphorylated tau as well as neurofibrillary tangles.

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References

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Further Reading

Papers

  1. Hoe HS, Freeman J, Rebeck GW. Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons. Mol Neurodegener. 2006;1:18. PubMed.
  2. Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science. 2007 May 4;316(5825):750-4. PubMed.