Antibody

Synapsin I

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Clonality: polyclonal
Host: Rabbit
Source: Chemicon and Upstate are Millipore
Cat# AB1543
Reference:
Tampellini, 2007
Stevens, 2007
Nakamoto, 2007
(both, unknown formulation)
Formulation: liquid, serum, no preservative
Reactivity:
Reacts in: Bovine, Human, Mouse, Rat

Immunogen/Epitope

immunogen = synapsin I (mixture of Ia & Ib) purified from bovine brain

Specificity

Synapsin I (Mr of 80,000 and 77,000)

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References

Paper Citations

  1. Tampellini D, Magrané J, Takahashi RH, Li F, Lin MT, Almeida CG, Gouras GK. Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem. 2007 Jun 29;282(26):18895-906. PubMed.
  2. Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, Sher A, Litke AM, Lambris JD, Smith SJ, John SW, Barres BA. The classical complement cascade mediates CNS synapse elimination. Cell. 2007 Dec 14;131(6):1164-78. PubMed.
  3. Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. PubMed.

Further Reading

No Available Further Reading