Antibody

Presenilin-1

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Clonality: polyclonal
Host: Rabbit
Source: Cell Signaling
Cat# 3622
Reference:
Green, 2008
Formulation: affinity purified, liquid, HEPES, BSA, glycerol
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = syntheticpeptide (KLH coupled) corr. to residues arround valine 293 of human PS-1)

Specificity

endogenous levels of the C-terminal fragment of PS-1 (~22 kDa) and full length protein (55 kDa) to a lesser extent

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References

Paper Citations

  1. Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, Laferla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol. 2008 Jun 30;181(7):1107-16. PubMed.

Further Reading

No Available Further Reading