Antibody

Neurofilament NF-L (2F11)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Source: DAKO
Cat# M0762
References
Josephs, 2007
(unspecified formulation)
LaMonte, 2002
Formulation: supernatant, Tris, azide
Reactivity:
Reacts in: Cat, Dog, Rabbit, Cow, Horse, Opossum, Swine, Human, Mouse, Rat

Immunogen/Epitope

immunogen = neurofilament isolated from normal adult human brain

Specificity

labels neurons, neuronal processes, peripheral nerves, etc; cytoplasmic, 70 kDa unit (NF-L) in WB

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References

Paper Citations

  1. Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Dickson DW, Jack CR. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol. 2008 Feb;63(2):204-12. PubMed.
  2. LaMonte BH, Wallace KE, Holloway BA, Shelly SS, Ascaño J, Tokito M, Van Winkle T, Howland DS, Holzbaur EL. Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron. 2002 May 30;34(5):715-27. PubMed.

Further Reading

No Available Further Reading