Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Abcam
Cat# ab32216
References:
O'Connor, 2008
Wang, 2007
Formulation: liquid, BSA, borate buffered saline, azide, affinity purified
Reactivity:
Reacts in: Mouse, Rat
expect human, cow, cat, dog

Immunogen/Epitope

immunogen = synthetic peptide derived from within residues 950 to the C-terminus of human insulin degrading enzyme / IDE

Specificity

IDE

Comments / Questions

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References

Paper Citations

1. O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26;60(6):988-1009. PubMed.
2. Wang J, Ho L, Chen L, Zhao Z, Zhao W, Qian X, Humala N, Seror I, Bartholomew S, Rosendorff C, Pasinetti GM. Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease. J Clin Invest. 2007 Nov;117(11):3393-402. PubMed.

Further Reading

No Available Further Reading