Clonality: monoclonal
Host: Mouse
Isotype: IgG
Source: Chemicon and Upstate are Millipore
Cat# MAB5374
Reference:
Yang, 2008
Formulation: liquid, supernatant, no preservative
Reactivity:
Reacts in: Human
weaker reactivity with rat and mouse

Immunogen/Epitope

Immunogen = GST fusion protein from the first 256 amino acids from human huntingtin with the deletion of the polyglutamine tract

Specificity

Huntingtin protein (native and recomb.). Reacts with mutant huntingtin that express different numbers of repeats (82 to 150 glutamines), and different forms of mutant huntingtin.

Comments / Questions

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References

Paper Citations

1. Yang SH, Cheng PH, Banta H, Piotrowska-Nitsche K, Yang JJ, Cheng EC, Snyder B, Larkin K, Liu J, Orkin J, Fang ZH, Smith Y, Bachevalier J, Zola SM, Li SH, Li XJ, Chan AW. Towards a transgenic model of Huntington's disease in a non-human primate. Nature. 2008 Jun 12;453(7197):921-4. PubMed.

Further Reading

No Available Further Reading