Antibody

GFAP

Clonality: polyclonal
Host: Rabbit
Methods: IC
Source: DAKO
cat# Z0334
References:
Wang, J, 2010
Wegorzewska, 2009
Grathwohl, 2009
He, 2009
Chu, 2009
Maier, 2008
Breunig, 2007
Ding, 2008
Shaftel, 2007
Formulation: liquid, serum, Ig fract, saline, azide<br />Also available ready-to-use, IR524, 60 tests, or IS524, 30 tests
Reactivity:
Reacts in: Cat, Dog, Cow, Sheep, Human, Mouse, Rat

Immunogen/Epitope

GFAP isolated from cow spinal cord

Specificity

stains astrocytes, ependymal cells, Schwann cells, satellite cells and enteric glial cells; cytoplasmic

Note

diagnosis

Comments / Questions

No Available Comments

Make a comment or submit a question

To make a comment you must login or register.

References

Paper Citations

  1. . Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6498-503. Epub 2010 Mar 15 PubMed.
  2. . TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18809-14. Epub 2009 Oct 15 PubMed.
  3. . Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci. 2009 Nov;12(11):1361-3. PubMed.
  4. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  5. . A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2097-103. PubMed.
  6. . Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. J Neurosci. 2008 Jun 18;28(25):6333-41. PubMed.
  7. . Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20558-63. PubMed.
  8. . Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci. 2008 Nov 5;28(45):11622-34. PubMed.
  9. . Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest. 2007 Jun;117(6):1595-604. PubMed.

Further Reading

No Available Further Reading