Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Cayman Chemical
Cat# 160116
Reference:
Heneka, 2010
Formulation: purified antiserum, IgG, lyophilized
Reactivity:
Reacts in: Ovine, Rabbit, Human, Monkey, Guinea Pig, Mouse, Rat
expect bovine and canine

Immunogen/Epitope

immunogen = synthetic peptide from the murine/rat COX-2 sequence, aa 584-598 (SHSRLDDINPTVLIK)

Specificity

COX-2; no cross reaction with COX-1

Comments / Questions

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References

Paper Citations

1. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.

Further Reading