Antibody

CD31 /PECAM-1 (MEC 13.3)

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Clonality: monoclonal
Host: Rat
Isotype: IgG2a,κ
Source: BD Pharmingen
Cat# 550274
Reference:
Bell, 2009
Ajami, 2008
Formulation: aqueous buffered solution, BSA, goat serum, azide
Reactivity:
Reacts in: Mouse

Immunogen/Epitope

immunogen = 129/Sv mouse-derived endothelioma cell line tEnd.1

Specificity

reacts with CD31; stains endothelial cells on small and large blood vessels; inhibits a variety of in vitro and in vivo functions mediated by CD31

Note

not IH-formalin

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References

Paper Citations

  1. Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol. 2009 Feb;11(2):143-53. PubMed.
  2. Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007 Dec;10(12):1538-43. PubMed.

Further Reading

No Available Further Reading