Antibody

CD31 /PECAM-1 (MEC 13.3)

Clonality: monoclonal
Host: Rat
Isotype: IgG2a
Methods: IH
Source: BD Pharmingen
Cat# 550274
Reference:
Bell, 2009
Ajami, 2008
Formulation: aqueous buffered solution, BSA, goat serum, azide
Reactivity:
Reacts in: Mouse

Immunogen/Epitope

immunogen = 129/Sv mouse-derived endothelioma cell line tEnd.1

Specificity

reacts with CD31; stains endothelial cells on small and large blood vessels; inhibits a variety of in vitro and in vivo functions mediated by CD31

Note

not IH-formalin

Comments / Questions

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References

Paper Citations

  1. . SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol. 2009 Feb;11(2):143-53. PubMed.
  2. . Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007 Dec;10(12):1538-43. PubMed.

Further Reading

No Available Further Reading