Antibody
Beta- Secretase
Quick Links
Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: A B R - Thermo Scientific
cat# PA1-756
references:
Fukumoto, 2002
Puglielli, 2001
discontinued
Formulation: affinity purified, azide
Reactivity:
Reacts in: Human
Immunogen/Epitope
immunogen = synthetic peptide, aa. 122-131 of human β-secretase 1
Specificity
β-secretase 1
References
Paper Citations
- Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol. 2002 Sep;59(9):1381-9. PubMed.
- Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol. 2001 Oct;3(10):905-12. PubMed.
Further Reading
News
- Québec: Teasing Out the Function of TDP-43
- Research Brief: TDP-43 Knockout Lethal, Hets Have Motor Symptoms
- Honolulu: TDP-43 Gets a Place in the Sun
- Going Nuclear: First Function for FUS Mutants
- Going Wild About the Latest TDP-43 Mouse Models
- TDP-43: Modified and On the Move
- ALS Research: More TDP-43, and Peripherin No Longer in Periphery?
- Meet the First Published TDP-43 Mouse
- Latest TDP-43 Mouse Unites ALS and SMA Pathways
- Paper Alert: Malformed Mitochondria in the Latest TDP-43 Mouse
- San Diego: TDP-43 Targets Loom Large—But Where’s the Bull’s Eye?
Comments / Questions
No Available Comments
Make a comment or submit a question
To make a comment you must login or register.