Antibody

Anti-phospho TDP-43 (ser409/410) (1D3)

Clonality: monoclonal
Host: Rat
Isotype: IgG2ak
Methods: ELISA, IB, IH, WB
Source: Millipore
Catalog #: MABN14
Formulation: Purified in buffer containing 0.1 M Tris glycine with 0.05% sodium azide
Reactivity:
Reacts in: Human
Availability: Confirmed Oct 2014

Immunogen/Epitope

Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at serine 409 and 410.

Specificity

This antibody recognizes human TDP-43 phosphorylated at serine 409 and 410.

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References

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Further Reading

Papers

  1. . The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS. Science. 2013 Mar 15;339(6125):1335-8. Epub 2013 Feb 7 PubMed.
  2. . Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem. 2009 Aug;110(3):1082-94. Epub 2009 Jun 9 PubMed.