Antibody

Amyloid Beta 40

Tools

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Clonality: kit
Host: Mouse
Source: Wako Chemicals
cat# 294-64701
Wako Kit Page
(see also
Cat# 298-62501)
References:
Kitazume, 2010
Hashimoto, 2010
Formulation: 96 tests:<br />BNT77/BA27(Fab')<sub>2</sub>, HRP conj. antibodies from Takeda Chemical Industries.<br />range: 1.0~100 pmol/L.<br />Achieved stable antigen-antibody reaction
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

achieves more stable antigen-antibody reactions by using F(ab' )2 fragment of the labeled antibody BA27, which recognizes the C-terminal of beta Amyloid 40, while the nonspecific binding is remaining to be reduced

Specificity

detects the C-terminal of Aβ (1-40) and Aβ (x-40)

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References

Antibody Citations

  1. Amyloid Beta 1-40

Paper Citations

  1. Kitazume S, Tachida Y, Kato M, Yamaguchi Y, Honda T, Hashimoto Y, Wada Y, Saito T, Iwata N, Saido T, Taniguchi N. Brain endothelial cells produce amyloid {beta} from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form. J Biol Chem. 2010 Dec 17;285(51):40097-103. PubMed.
  2. Hashimoto M, Bogdanovic N, Volkmann I, Aoki M, Winblad B, Tjernberg LO. Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Abeta42 and Alzheimer's disease neuropathology. Acta Neuropathol. 2010 May;119(5):543-54. PubMed.

External Citations

  1. Kit Page

Further Reading

No Available Further Reading