Antibody

Akt

Tools

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Clonality: polyclonal
Host: Rabbit
Source: Cell Signaling
Cat# 9272
References:
Gatchel, 2008
Papadia, 2008
Rockenstein, 2007
Formulation: HEPES, NaCl, BSA, glycerol Protein A and affinity purified
Reactivity:
Reacts in: Dog, Chicken, Pig, Human, Hamster, Mouse, Rat, Drosophila

Immunogen/Epitope

Immunogen = synthetic peptide derived from C-terminal sequence of mouse Akt

Specificity

endogenous levels of Akt1, Akt2, Akt3; no cross reaction with related proteins

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References

Paper Citations

  1. Gatchel JR, Watase K, Thaller C, Carson JP, Jafar-Nejad P, Shaw C, Zu T, Orr HT, Zoghbi HY. The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1291-6. PubMed.
  2. Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci. 2008 Apr;11(4):476-87. PubMed.
  3. Rockenstein E, Torrance M, Adame A, Mante M, Bar-On P, Rose JB, Crews L, Masliah E. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. J Neurosci. 2007 Feb 21;27(8):1981-91. PubMed.

Further Reading

No Available Further Reading