Antibody

α Adaptin (AP6)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: A B R - Thermo Scientific
Cat# MA1-064
Reference:
Ferguson, 2007
Formulation: liquid, PBS, azide, purified
Reactivity:
Reacts in: Bovine, Primate (various), Human, Hamster, Mouse, Rat

Immunogen/Epitope

Immunogen = purified adaptors

Specificity

detects the products of both alpha-adaptin genes, alphaA and alphaC, as well as an alternatively spliced isoform of alphaA found in neurons; recognizes an ~100 kDa doublet representing the two isoforms of alpha-adaptin in rat brain

Note

blockade of endocytosis

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References

Paper Citations

  1. Ferguson SM, Brasnjo G, Hayashi M, Wölfel M, Collesi C, Giovedi S, Raimondi A, Gong LW, Ariel P, Paradise S, O'Toole E, Flavell R, Cremona O, Miesenböck G, Ryan TA, De Camilli P. A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science. 2007 Apr 27;316(5824):570-4. PubMed.

Further Reading

No Available Further Reading