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New AD Data Standard: FDA Wants It; Will Trial Groups Use It?
RESEARCH NEWS 2011-11-03 Research News Try combining random pages from a novel and then figuring out the plot. That is similar to what regulatory agencies are up against when they analyze results from drug applications for Alzheimer’s disease (AD), with each company using its own
Hormone Replacement Therapy Latest Entry to AlzRisk Database
RESEARCH NEWS 2011-11-03 Research News Despite almost two decades of research, it is not yet clear how hormone replacement therapy affects a woman’s risk of getting Alzheimer’s disease. The curators of the AlzRisk database, hosted by Alzforum, undertook a review of what the liter
Excess Glutamate, Low Oxygen: Can Common Enzyme Mask Effects?
RESEARCH NEWS 2011-11-03 Research News Drought and deluges are rarely good. In the brain, too little oxygen or too much of the neurotransmitter glutamate are both bad news. But there is a potential savior. The enzyme nicotinamide mononucleotide adenylyl transferase (Nmnat) is kno
PAPER Ham A, Lee SJ, Shin J, Kim KH, Mar W
Regulatory effects of costunolide on dopamine metabolism-associated genes inhibit dopamine-induced apoptosis in human dopaminergic SH-SY5Y cells.
Neurosci Lett. 2012 Jan 24;507(2):101-5. PubMed: 22040670PAPER Liu P, Guo J, Qi Z
Formaldehyde suppresses neuronal apoptosis via inhibition of outward K(+) currents in rat hippocampus.
Can J Physiol Pharmacol. 2011 Nov 1; PubMed: 22040012PAPER Chang JR, Ghafouri M, Mukerjee R, Bagashev A, Chabrashvili T, Sawaya BE
Role of p53 in Neurodegenerative Diseases.
Neurodegener Dis. 2011 Oct 28; PubMed: 22042001PAPER Kim TW, Moon Y, Kim K, Lee JE, Koh HC, Rhyu IJ, Kim H, Sun W
Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases.
PLoS One. 2011;6(10):e25346. PubMed: 22043283PAPER Sakaguchi T, Irie T, Kawabata R, Yoshida A, Maruyama H, Kawakami H
Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation.
Neurosci Lett. 2011 Nov 21;505(3):279-81. PubMed: 22040667PAPER Patki G, Lau YS
Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease.
Neurosci Lett. 2011 Nov 21;505(3):268-72. PubMed: 22040668PAPER Di Liberto V, Mäkelä J, Korhonen L, Olivieri M, Tselykh T, Mälkiä A, Do Thi H, Belluardo N, Lindholm D, Mudò G
Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice.
Neuropharmacology. 2012 Feb;62(2):1011-8. PubMed: 22041555PAPER Binda C, Milczek EM, Bonivento D, Wang J, Mattevi A, Edmondson DE
Lights and shadows on monoamine oxidase inhibition in neuroprotective pharmacological therapies.
Curr Top Med Chem. 2011 Nov;11(22):2788-96. PubMed: 22039878PAPER Acharya MM, Roa DE, Bosch O, Lan ML, Limoli CL
Stem cell transplantation strategies for the restoration of cognitive dysfunction caused by cranial radiotherapy.
J Vis Exp. 2011;(56) PubMed: 22042021PAPER Keck-Wherley J, Grover D, Bhattacharyya S, Xu X, Holman D, Lombardini ED, Verma R, Biswas R, Galdzicki Z
Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes.
Dev Neurosci. 2011;33(5):451-67. PubMed: 22042248PAPER Chiechio S, Nicoletti F
Metabotropic glutamate receptors and the control of chronic pain.
Curr Opin Pharmacol. 2011 Oct 29; PubMed: 22040745Current Filters
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