Get Newsletter
Alzheimer Research Forum - Networking for a Cure Alzheimer Research Forum - Networking for a CureAlzheimer Research Forum - Networking for a Cure
  
What's New HomeContact UsHow to CiteGet NewsletterBecome a MemberLogin          
Papers of the Week
Current Papers
ARF Recommends
Milestone Papers
Search All Papers
Search Comments
News
Research News
Drug News
Conference News
Research
AD Hypotheses
  AlzSWAN
  Current Hypotheses
  Hypothesis Factory
Forums
  Live Discussions
  Virtual Conferences
  Interviews
Enabling Technologies
  Workshops
  Research Tools
Compendia
  AlzGene
  AlzRisk
  Antibodies
  Biomarkers
  Mutations
  Protocols
  Research Models
  Video Gallery
Resources
  Bulletin Boards
  Conference Calendar
  Grants
  Jobs
Early-Onset Familial AD
Overview
Diagnosis/Genetics
Research
News
Profiles
Clinics
Drug Development
Companies
Tutorial
Drugs in Clinical Trials
Disease Management
About Alzheimer's
  FAQs
Diagnosis
  Clinical Guidelines
  Tests
  Brain Banks
Treatment
  Drugs and Therapies
Caregiving
  Patient Care
  Support Directory
  AD Experiences
Community
Member Directory
Researcher Profiles
Institutes and Labs
About the Site
Mission
ARF Team
ARF Awards
Advisory Board
Sponsors
Partnerships
Fan Mail
Support Us
Return to Top
Research News
 
Grasping at the Future of Brain-Computer Interfaces
19 May 2012. In a slow-mo game of mental Whack-a-Mole, two paralyzed people, using only their thoughts and an implanted brain sensor, manipulated a robotic arm to grasp foam balls...
 
Soluble Aβ Takes Blame for Hyperactive Neurons in Mouse Brain
18 May 2012. Scientists observe a mix of abnormally silent and overactive neurons in Alzheimer's disease brains, especially in the cortex...
 
Blast Anatomy—Chronic Traumatic Encephalopathy in Military Vets
18 May 2012. Since soldiers stumbled out of World War I with panic attacks, nightmares, and other signs of shell shock, debate has raged over the nature of this trauma...
 
ApoE4 Makes Blood Vessels Leak, Could Kick Off Brain Damage
17 May 2012. New evidence appearing in today’s Nature implicates the ApoE4 allele, the primary genetic risk factor for late-onset AD, as a prime culprit in damaging brain blood vessels...
 
GO TO ALL RESEARCH NEWS  
 
 
In the spotlight

Prevention Trial in Familial AD To Test Genentech Antibody
The first asymptomatic treatment trial of an investigational Alzheimer's immunotherapy got the go-ahead when a three-way collaboration among the biotech company Genentech, the federal government, and private philanthropy
was forged to fund it and to provide both drug and expertise.

The five-year trial will test the antibody crenezumab in Colombian carriers of the Paisa mutation in presenilin-1, and in some U.S. carriers of other presenilin and APP mutations. At the Alzheimer's Disease Research Summit 2012 in Washington, D.C., NIH Director Francis Collins announced that the trial, as well as a second trial of intranasal insulin in MCI, were part of the National Plan to Address Alzheimer’s Disease, which HHS Secretary Kathleen Sebelius released on 15 May 2012.
NIH Director Announces $100M Prevention Trial of Genentech Antibody
Q&A With Genentech Lead Scientist on API Trial Ryan Watts

Grasping at the Future of Brain-Computer Interfaces

Click image to view video
“I think about moving my hand and wrist…it feels natural.” The woman in this video is paralyzed. She talks about her experience controlling the robotic arm via a sensor in her brain. Using this brain-computer interface, she is serving herself a sip of coffee for the first time since her stroke 15 years ago.

The research is part of the BrainGate pilot trial to restore motor ability to people who have lost a limb or are paralyzed from injury or disease. The coffee exercise and another target-grabbing activity represent the first time people using a computer interface have completed complex, three-dimensional motions. Read the full story. Video courtesy of Nature

DIAN Progress Update
At the Alzheimer's Disease Research Summit 2012, being held 14-15 May at the National Institutes of Health, speakers cited the Dominantly Inherited Alzheimer Network (DIAN) as an example of the kind of integrated observational and treatment initiative that advances the field. Click for highlights from DIAN's most recent trial preparation meeting on 15 April 2012.

DIAN Grows, Gets Ready for Therapeutic Trials
What Sayeth the Regulator? Q&A With Rusty Katz
Read a PDF of the series.
 
 
What's New

Comments - Posted 21 May 2012
Read remarks by Vahram (Harry) Haroutunian, Pavel Katsel about Zamanian JL et al.
PAPER: Genomic analysis of reactive astrogliosis.
 
Grants Update - Posted 18 May 2012
Program: National Institute on Aging Analysis of Alzheimer's Disease Genome Sequencing Project Data [U19]
Funds: up to $2,000,000 direct cost per award
Deadline(s): Letter of Intent: 8 Jul 2012; Application: 7 Aug 2012; 25 Jan 2013; 25 May 2013.
 
Comments - Posted 18 May 2012
Read remarks by Michael Weiner about Gandy S et al.
PAPER: APOE {varepsilon}4 Status and Traumatic Brain Injury on the Gridiron or the Battlefield.
 
Comments - Posted 18 May 2012
Read remarks by Joachim Herz about Bell RD et al.
NEWS: ApoE4 Makes Blood Vessels Leak, Could Kick Off Brain Damage
 
Comments - Posted 18 May 2012
Read remarks by Peter Davies
NEWS: NIH Director Announces $100M Prevention Trial of Genentech Antibody
 
Comments - Posted 18 May 2012
Read remarks by Douglas Galasko about Gandy S et al.
PAPER: APOE {varepsilon}4 Status and Traumatic Brain Injury on the Gridiron or the Battlefield.
 
Comments - Posted 18 May 2012
Read remarks by Rudy Tanzi about Gandy S et al.
PAPER: APOE {varepsilon}4 Status and Traumatic Brain Injury on the Gridiron or the Battlefield.
 
Comments - Posted 18 May 2012
Read remarks by Eric Nauman about Goldstein LE et al.
PAPER: Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

SEE MORE  
Print this page
Email this page
Alzforum News
Papers of the Week
Text size
Share & Bookmark
Forum Calendar

Check out our most recent Webinar: “Network Epicenters” in Healthy Connectome Predict Dementia.

Listen to the recording of Claudia Kawas' HAI keynote lecture at our ongoing Forum Webinar: AD in the Oldest Old—What Does Aβ Have to Do With It?

AlzGene
PDGene
SZGene
MSGene
ALSGene
An up-to-date collection of all published genetic association studies.
Coalition Against Major Diseases (CAMD)
Visit C-Path's Coalition Against Major Diseases to learn about its collaborative efforts in Alzheimer's and Parkinson's.
C-Path
AlzRisk: An AD Epidemiology Database
The AlzRisk Epidemiology Database provides a publicly available collection of published studies on the impact of putative environmental risk factors and protective factors related to Alzheimer disease in longitudinal cohort studies.
Topics in Neurodegeneration
Download Powerpoint Presentations created by top experts in neurodegenerative disease research. Available for educational or personal use. Edited by Daniel M. Michaelson, PhD, and Tobias Hartmann, PhD.

Copyright © 1996-2012 Alzheimer Research Forum Terms of Use How to Cite Privacy Policy Disclaimer Disclosure Copyright
wma logoadadad