This New York Academy of Sciences symposium, to be held 10 December 2013, explores how efforts to better integrate our
understanding of neuritic plaques and neurofibrillary tangles—the two hallmark pathologies of Alzheimer's disease—have led to a "truce" between former rivals in the quest for therapies. Image courtesy of New York Academy of Sciences
Comments - Posted 2 December 2013 Read remarks by Takaomi Saido about Kalimo H et al. PAPER: The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ
Comments - Posted 2 December 2013 Read remarks by Jurgen Goetz about Henderson SJ et al. PAPER: Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β
Comments - Posted 2 December 2013 Read remarks by Jurgen Goetz about Polydoro M et al. PAPER: Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
Comments - Posted 30 November 2013 Read remarks by David Holtzman about Hudry E et al. PAPER: Gene transfer of human apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.
The AlzRisk Epidemiology Database provides a publicly available collection of published studies on the impact of putative environmental risk factors and protective factors related to Alzheimer disease in longitudinal cohort studies.