332015 RESULTS
COMMENT Aβ oligomers bind to multiple proteins and have diverse effects in cell culture and animal models of the disease, depending on a plethora of variables such as oligomer species, length of exposure of neurons to oligomers, mutations harbored by transgenic m
PAPER Rust MB, Gurniak CB, Renner M, Vara H, Morando L, Görlich A, Sassoè-Pognetto M, Banchaabouchi MA, Giustetto M, Triller A, Choquet D, Witke W
RESEARCH NEWS 2013-09-20 Research News The cortex is a remarkably adaptable structure. Deprive a small region of input, and axons from neighboring areas undergo exuberant outgrowth and pruning, in order to reactivate the freed-up real estate. While scientists know what causes new
COMMUNITY NEWS 2013-09-20 Community News The National Institutes of Health announced September 18 that it will allocate $45 million in new funding to advance Alzheimer’s research. The bulk of the money will help support therapeutic prevention trials in cognitively healthy populati
RESEARCH NEWS 2013-09-20 Research News The list of claimed Aβ receptors is growing, and the latest addition hails from the immune system. In the September 20 Science, Carla Shatz of Stanford University, Palo Alto, California, and collaborators elsewhere report Aβ oligomer binding
RESEARCH NEWS 2013-09-20 Research News Researchers attempting to spy tau pathology in the living human brain have come up with a trio of options. In the September 18 Neuron, brain imagers from the National Institute of Radiological Sciences in Chiba, Japan, present the first publ
Australia
RESEARCH NEWS 2013-09-19 Research News Scientists have pinpointed many gene variants that heighten a person’s risk for Parkinson's, but rarely have they happened upon deletions of whole chromosome fragments. Now, researchers led by Anne Bassett, Centre for Addiction and Ment
RESEARCH NEWS 2013-09-19 Research News The amyotrophic lateral sclerosis gene FUS mends broken DNA strands, according to a paper in the September 15 Nature Neuroscience online. FUS has also been linked to frontotemporal dementia. As originally reported by Alzforum at a Keystone S
University Hospitals of ClevelandUnited States
COMMENT The authors provide convincing evidence that links chromosome 22q11 deletions to PD. Although patients with 22q11 and LRRK2 mutations share many neuropathological abnormalities, it remains to be determined whether they follow similar pathogenic pathways.
PAPER Anichtchik O, Calo L, Spillantini MG
PAPER Stewart T, Sui YT, Gonzalez-Cuyar LF, Wong DT, Akin DM, Tumas V, Aasly J, Ashmore E, Aro P, Ginghina C, Korff A, Zabetian CP, Leverenz JB, Shi M, Zhang J
PAPER Fratta P, Collins T, Pemble S, Nethisinghe S, Devoy A, Giunti P, Sweeney MG, Hanna MG, Fisher EM
PAPER Le Ber I, Camuzat A, Guerreiro R, Bouya-Ahmed K, Bras J, Nicolas G, Gabelle A, Didic M, De Septenville A, Millecamps S, Lenglet T, Latouche M, Kabashi E, Campion D, Hannequin D, Hardy J, Brice A,
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