PAPER Ferreri F, Määttä S, Vecchio F, Curcio G, Ferrarelli F
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PAPER Dezor M, Dorszewska J, Florczak J, Kempisty B, Jaroszewska-Kolecka J, Rozycka A, Polrolniczak A, Bugaj R, Jagodzinski PP, Kozubski W
Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-αlpha proteins in peripheral lymphocytes of patients with Alzheimer's disease.
Folia Neuropathol. 2011;49(2):123-31. PubMed: 21845541PAPER Engedal K, Barca ML, Laks J, Selbaek G
Depression in Alzheimer's disease: specificity of depressive symptoms using three different clinical criteria.
Int J Geriatr Psychiatry. 2011 Sep;26(9):944-51. PubMed: 21845597PAPER Devanand DP, Pelton GH, Cunqueiro K, Sackeim HA, Marder K
A 6-month, randomized, double-blind, placebo-controlled pilot discontinuation trial following response to haloperidol treatment of psychosis and agitation in Alzheimer's disease.
Int J Geriatr Psychiatry. 2011 Sep;26(9):937-43. PubMed: 21845596PAPER Guo X, Wu X, Ren L, Liu G, Li L
Epigenetic mechanisms of amyloid-β production in anisomycin-treated SH-SY5Y cells.
Neuroscience. 2011 Oct 27;194:272-81. PubMed: 21843603PAPER Xiong F, Leonov S, Howard AC, Xiong S, Zhang B, Mei L, McNeil P, Simon S, Xiong WC
Receptor for advanced glycation end products (RAGE) prevents endothelial cell membrane resealing and regulates F-actin remodeling in a beta-catenin-dependent manner.
J Biol Chem. 2011 Oct 7;286(40):35061-70. PubMed: 21844192Lawrence Rajendran on ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.
COMMENT This elegant cell biology study adds another important piece to the puzzle of how endocytosis controls amyloid production. A few years ago, we showed that APP and BACE are internalized into early endosomes where β cleavage occurs (Rajendran et al., 2006).
Jed Johnson
Nanofiber SolutionsColumbus, United States
Gopika Nigam
Dr Babasaheb Ambedkar Marathwada UniversityAURANGABAD, India
PAPER Davey MJ, Sayers TJ, Baum H
Letter: Autoantigenicity of subcellular membranes.
Lancet. 1975 Jan 25;1(7900):228-9. PubMed: 47467PAPER Rohrer JD
Structural brain imaging in frontotemporal dementia.
Biochim Biophys Acta. 2011 Jul 30; PubMed: 21839829PAPER Burrell JR, Kiernan MC, Vucic S, Hodges JR
Motor neuron dysfunction in frontotemporal dementia.
Brain. 2011 Sep;134(Pt 9):2582-94. PubMed: 21840887PAPER Hughes LE, Nestor PJ, Hodges JR, Rowe JB
Magnetoencephalography of frontotemporal dementia: spatiotemporally localized changes during semantic decisions.
Brain. 2011 Sep;134(Pt 9):2513-22. PubMed: 21840892PAPER Kim HT, So JH, Jung SH, Ahn DG, Koh W, Kim NS, Kim SH, Lee S, Kim CH
Cug2 is essential for normal mitotic control and CNS development in zebrafish.
BMC Dev Biol. 2011;11:49. PubMed: 21838932PAPER Al-Saif A, Al-Mohanna F, Bohlega S
A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis.
Ann Neurol. 2011 Dec;70(6):913-9. PubMed: 21842496Current Filters
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