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Miami: Age and Amyloid—What Has ApoE Got to Do With It?

CONFERENCE COVERAGE 2012-03-02 Conference Coverage At this stage of Alzheimer's disease research, scientists know that APP or presenilin mutations and the risk gene ApoE4 have two things in common. Both bring down the carrier’s age of disease onset, ApoE4 less drastically than the

Research Brief: Is Rare Amyloid Disorder Autoimmune Disease?

RESEARCH NEWS 2012-03-02 Research News In a rare condition known as amyloid-β-related angiitis (ABRA), buildup of amyloid in the brain vasculature (cerebral amyloid angiopathy) is accompanied by swelling in the small- and medium-sized arteries of the cortices and in the membranes

Astrocyte ATP, Transmembrane Chemokine Drive Neuroprotection

RESEARCH NEWS 2012-03-02 Research News Astrocytes—the star-shaped cells that support neurons in the brain—seem two-faced. While they can trigger harmful neuroinflammation, astrocytes also secrete molecules that may help curb that destruction. Two papers in this week’s Journal of

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