NEALS: Sharing Among ALS Researchers and Participants

RESEARCH NEWS 2011-10-31 Research News In the world of neurodegenerative disease trials, no researcher can afford to be an island. Willing participants—particularly with a rare disease such as amyotrophic lateral sclerosis (ALS)—are scattered so sparsely across the country that a

Fnu Azra

University of Illinois at Urbana Champaign
URBANA, United States

PAPER Del Rey A, Yau HJ, Randolf A, Centeno MV, Wildmann J, Martina M, Besedovsky HO, Apkarian AV

Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus.

Pain. 2011 Dec;152(12):2827-35. PubMed: 22033365

PAPER Swanepoel T, Harvey BH, Harden LM, Laburn HP, Mitchell D

Simulated systemic recurrent Mycoplasma infection in rats induces recurrent sickness responses without residual impairment in spatial learning and memory.

Physiol Behav. 2012 Feb 1;105(3):800-8. PubMed: 22032906

PAPER Qu M, Zhou Z, Chen C, Li M, Pei L, Chu F, Yang J, Wang Y, Li L, Liu C, Zhang L, Zhang G, Yu Z, Wang D

Lycopene protects against trimethyltin-induced neurotoxicity in primary cultured rat hippocampal neurons by inhibiting the mitochondrial apoptotic pathway.

Neurochem Int. 2011 Dec;59(8):1095-103. PubMed: 22032970

PAPER Coulthart MB, Jansen GH, Olsen E, Godal DL, Connolly T, Choi BC, Wang Z, Cashman NR

Diagnostic accuracy of cerebrospinal fluid protein markers for sporadic Creutzfeldt-Jakob disease in Canada: a 6-year prospective study.

BMC Neurol. 2011;11:133. PubMed: 22032272

PAPER Odagiri S, Mori F, Tanji K, Kuroda N, Wakabayashi K

Immunohistochemical study of microscopic globular bodies of normal human brain.

Biomed Res. 2011 Oct;32(5):337-42. PubMed: 22033303

PAPER Huang Z, Xu Z, Wu Y, Zhou Y

Determining nuclear localization of alpha-synuclein in mouse brains.

Neuroscience. 2011 Dec 29;199:318-32. PubMed: 22033456

PAPER Soon CP, Donnelly PS, Turner BJ, Hung LW, Crouch PJ, Sherratt NA, Tan JL, Lim NK, Lam L, Bica L, Lim S, Hickey JL, Morizzi J, Powell A, Finkelstein DI, Culvenor JG, Masters CL, Duce J, White AR, Barnham KJ, Li QX

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model.

J Biol Chem. 2011 Dec 23;286(51):44035-44. PubMed: 22033929

PAPER Kocerha J, Kouri N, Baker M, Finch N, Dejesus-Hernandez M, Gonzalez J, Chidamparam K, Josephs KA, Boeve BF, Graff-Radford NR, Crook J, Dickson DW, Rademakers R

Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations.

BMC Genomics. 2011;12:527. PubMed: 22032330

PAPER Adhikari A, Topiwala MA, Gordon JA

Single units in the medial prefrontal cortex with anxiety-related firing patterns are preferentially influenced by ventral hippocampal activity.

Neuron. 2011 Sep 8;71(5):898-910. PubMed: 21903082

PAPER Bendotti C, Marino M, Cheroni C, Fontana E, Crippa V, Poletti A, De Biasi S

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: Implication for protein aggregation and immune response.

Prog Neurobiol. 2011 Oct 20; PubMed: 22033150

PAPER Petzold GC, Murthy VN

Role of astrocytes in neurovascular coupling.

Neuron. 2011 Sep 8;71(5):782-97. PubMed: 21903073

PAPER Hou Y, Yang Q, Zhou L, Du X, Li M, Yuan M, Zhou Z, Li Z

Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway.

Can J Physiol Pharmacol. 2011 Nov;89(11):801-9. PubMed: 22032649

PAPER Machado MC, Lopes GH, Marchini L

Oral health of Alzheimer's patients in São José dos Campos, Brazil.

Geriatr Gerontol Int. 2011 Oct 27; PubMed: 22032653