PAPER Tiribuzi R, Orlacchio A, Crispoltoni L, Maiotti M, Zampolini M, De Angeliz M, Mecocci P, Cecchetti R, Bernardi G, Datti A, Martino S

Lysosomal β-galactosidase and β-hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimer's disease and type 2 diabetes mellitus.

J Alzheimers Dis. 2011;24(4):785-97. PubMed: 21321400

PAPER Oliveri V, Puglisi A, Vecchio G

New conjugates of β-cyclodextrin with manganese(III) salophen and porphyrin complexes as antioxidant systems.

Dalton Trans. 2011 Mar 28;40(12):2913-9. PubMed: 21321734

PAPER Schilling T, Eder C

Amyloid-β-induced reactive oxygen species production and priming are differentially regulated by ion channels in microglia.

J Cell Physiol. 2011 Dec;226(12):3295-302. PubMed: 21321937

PAPER O'Sullivan SS, Johnson M, Williams DR, Revesz T, Holton JL, Lees AJ, Perry EK

The effect of drug treatment on neurogenesis in Parkinson's disease.

Mov Disord. 2011 Jan;26(1):45-50. PubMed: 21322018

PAPER Omura Y, Chen Y, Lermand O, Jones M, Duvvi H, Shimotsuura Y

Effects of transcutaneous electrical stimulation (1 pulse/sec) through custom-made disposable surface electrodes covering Omura's ST36 area of both legs on normal cell telomeres, oncogen C-fosAb2, integrin alpha5beta1, chlamydia trachomatis, etc. in breas

Acupunct Electrother Res. 2010;35(3-4):147-85. PubMed: 21319603

PAPER Gulyás B, Vas A, Tóth M, Takano A, Varrone A, Cselényi Z, Schain M, Mattsson P, Halldin C

Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine.

Neuroimage. 2011 Jun 1;56(3):1111-21. PubMed: 21320609

PAPER Kudo LC, Parfenova L, Ren G, Vi N, Hui M, Ma Z, Lau K, Gray M, Bardag-Gorce F, Wiedau-Pazos M, Hui KS, Karsten SL

Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice.

Hum Mol Genet. 2011 May 1;20(9):1820-33. PubMed: 21320871

PAPER Lin FR, Metter EJ, O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L

Hearing loss and incident dementia.

Arch Neurol. 2011 Feb;68(2):214-20. PubMed: 21320988

PAPER Sojkova J, Driscoll I, Iacono D, Zhou Y, Codispoti KE, Kraut MA, Ferrucci L, Pletnikova O, Mathis CA, Klunk WE, O'Brien RJ, Wong DF, Troncoso JC, Resnick SM

In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults.

Arch Neurol. 2011 Feb;68(2):232-40. PubMed: 21320990

PAPER Barnes DE, Yaffe K

Accuracy of summary risk score for prediction of Alzheimer disease: better than demographics alone?

Arch Neurol. 2011 Feb;68(2):268; author reply 268-70. PubMed: 21321000

PAPER Meyer PT, Hellwig S, Amtage F, Rottenburger C, Sahm U, Reuland P, Weber WA, Hüll M

Dual-biomarker imaging of regional cerebral amyloid load and neuronal activity in dementia with PET and 11C-labeled Pittsburgh compound B.

J Nucl Med. 2011 Mar;52(3):393-400. PubMed: 21321269

PAPER Chang YL, Bondi MW, McEvoy LK, Fennema-Notestine C, Salmon DP, Galasko D, Hagler DJ, Dale AM,

Global clinical dementia rating of 0.5 in MCI masks variability related to level of function.

Neurology. 2011 Feb 15;76(7):652-9. PubMed: 21321338

Richard Smeyne

St. Jude Children’s Research Hospital
Memphis, United States

Ferroportin /SLC40A1

ANTIBODY polyclonal manufacturer Cat# LS-B1836 immunogen = synthetic peptide corresponding to N-terminal residues of human MTP1 (Metal transporter protein 1), conj. to KLH liquid, affinity purified, PBS, azide, glycerol detects ferroportin IgG Iron Related LifeSpa

Making It Stick—Tau Toxicity Linked to Aggregation Propensity

RESEARCH NEWS 2011-02-16 Research News Snarls of tau protein accumulate in Alzheimer’s disease and other dementias, but increasing evidence suggests that it is soluble tau that does the most harm. At the same time, new research indicates that the stickiness of tau, i.e., its abil