Antibody

β-APP (LN27)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Source: Zymed/ Invitrogen
Cat# 13-0200
References:
Dreses-Werringloer, 2008
Li, 2003
Formulation: liquid, purified, PBS, azide
Reactivity:
Reacts in: Human

Immunogen/Epitope

Immunogen = recombinant-β-APP695; epitope = first 200 aa in N-terminus

Specificity

all three forms of β-APP (APP695, 751, 770)

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References

Paper Citations

  1. Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, Siebert A, Jain A, Koppel J, Rovelet-Lecrux A, Hannequin D, Pasquier F, Galimberti D, Scarpini E, Mann D, Lendon C, Campion D, Amouyel P, Davies P, Foskett JK, Campagne F, Marambaud P. A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell. 2008 Jun 27;133(7):1149-61. PubMed.
  2. Li Y, Wang H, Wang S, Quon D, Liu YW, Cordell B. Positive and negative regulation of APP amyloidogenesis by sumoylation. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):259-64. PubMed.

Further Reading