Mind Your Magnesium—Oral Compound Boosts Cognition in Rats
While too little calcium can trigger bone problems, insufficient magnesium may spell trouble for your brain...
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While too little calcium can trigger bone problems, insufficient magnesium may spell trouble for your brain...
A fruit fly is joining the menagerie of TDP-43 animal models, bringing the power of <em>Drosophila</em> genetics to the lab bench...
NMDA receptors populate the synapse, where they participate in nerve signaling and promote cell survival pathways; but those same receptors can activate apoptosis...
It’s time to cut out the middleman—why go from fibroblasts, to induced pluripotent stem cells, to neurons, if one can skip straight to the payload?...
Though ApoE4 genotype has for years topped the list of genetic risk factors for AD, scientists grapple with how this allele makes people more prone to AD...
In an organ as highly vascular as the brain, optimal performance depends on keeping the plumbing shipshape...
When it comes to the synaptic toxicity and cognitive dysfunction in AD, a preponderance of evidence points to soluble oligomers of Aβ peptides as the main villains...
The Keystone Symposium at Copper Mountain, Colorado, was convened to discuss therapeutic approaches to Alzheimer disease besides those that target amyloid-β...
TDP-43, normally a mild-mannered nuclear protein, morphs into a cytoplasmic super villain in TDP-43 proteinopathies...
For stem cell therapies to work, it is not enough for a new neuron to settle down in the brain...
Researchers have, by and large, assumed that Aβ starts aggregating outside the cell...
Two studies revive the notion that it might be possible, quite literally, to catch a whiff of neurodegenerative disease before the body and mind slip away for good...
Through their research participation, the Reiswig extended family made possible the identification of presenilin 2 on chromosome 1...
The Alzforum presents a selection of some of the top ALS trial news of 2009—and looks ahead to 2010 and beyond...
<em>Drosophila</em> geneticists with an interest in neurodegeneration can now avail themselves of a new insect model...