One hundred years ago, in January of 1907, Alois Alzheimer published his landmark paper about Auguste D. This is a perfect time to sit back and contemplate the field’s past accomplishments and future challenges. The Alzforum editors have compiled some ...
See questions answered by Suzanne Hendrix As researchers push into the frontier of early-stage and preventative Alzheimer's disease clinical trials, they will have to measure whether a drug works in people who do not have dementia yet. Traditional ...
On 26 February 2009, we held a Webinar/Live Discussion with a slide presentation by Scott Small and subsequent panel discussion with legal ethicist Hank Greely at Stanford University, FDA representative Russell Katz, and clinician-researchers John (Wes) ...
On 19 April 2011, the National Institute on Aging (NIA) and the Alzheimer’s Association (AA) published new guidelines for the diagnosis of Alzheimer’s disease (AD) and its pre-dementia and preclinical phases (see ARF related news story on McKhann et al., ...
The amyloid hypothesis has dominated Alzheimer’s disease research for 25 years and generated major advances for the field. But as noted by Bart De Strooper and Eric Karran in the February 11 Cell, some of that new knowledge does not sit well with the ...
This Webinar recapped the latest research in this area. Michael Heneka of the University of Bonn, Germany, and Doug Feinstein of the University of Illinois, Chicago, gave presentations, and were joined in a panel discussion by Virgil Muresan, New Jersey ...
Giulio Maria Pasinetti led this live discussion on 5 March 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Background Reading by Giulio Maria Pasinetti et al. (pdf file: download free ...
Alzforum was pleased to partner with the journals Nature Medicine and Nature Reviews Drug Discovery in hosting a Webinar panel discussion on Thursday, 29 September 2011. At issue were a Perspective article by Dennis Selkoe on "Resolving controversies ...
John P. Blass and Gary Gibson led this live discussion on 15 April 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 15 April 2002. Participants: John Blass, Gary ...
Vikram Khurana and Ole Isacson led this live discussion on 29 June 2005. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live Discussion led by Ole Isacson and Vikram Khurana on 29 June ...
Searching for the wherewithal to push on with your work on a promising new Alzheimer therapy? The NIH offers funding for research support at every step of the process, from early drug discovery right through to phase 3 clinical trials, if you know where ...
Recent experience with an anti-TNFα drug has made scientists suspect that inhibiting this proinflammatory cytokine may hold promise as a protective treatment for diseases that feature neuroinflammation, such as Alzheimer's. Yet it is unclear how best ...
Anyone gazing into a crystal ball about the future health status of Americans should be quite worried about the rapid rise of obesity, diabetes, and related metabolic disorders. Not only do these conditions impose a large direct burden on the nation' ...
Cerebrospinal fluid (CSF) analysis has perhaps the strongest diagnostic and prognostic potential for Alzheimer disease to date, yet some think the field is not harnessing its full power because patients, doctors, and even some investigators harbor ...
As Tolstoy wrote in Anna Karenina, “Happy families are all alike; every unhappy family is unhappy in its own way.” The same might be said of the brain. Normal brains look and behave similarly, but those affected by different neurodegenerative diseases are ...
Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.