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Reducing the Risk of Alzheimer Disease

The topic is an apt one to launch the new year: what factors in daily life can reduce one's risk of Alzheimer's disease? To fire up your neural networks, you are invited to read the recent review (download pdf) by Kathryn Jedrziewski, Virginia ...

M1 Receptors Play a Central Role in AD Pathology and Cognition

Our thanks to Neuron for providing free access to this paper for the purposes of this live discussion. Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. M1 receptors play a central role in modulating AD-like pathology in ...

Webinar: The NeuronDB Knowledge Base

Gordon Shepherd and Kei Cheung from Yale University led this Web seminar. Our featured presenters provided an introduction to SenseLab, which is a long-standing database project to build integrated multidisciplinary models of neurons and neural systems. ...

Webinar: Axonopathy in Mouse Models of AD

Despite the availability of a wide range of animal models of Alzheimer disease, none of them are able to fully recapitulate all the facets of the disease. Axonopathy is a case in point. Although there has been renewed interest in the link between axonal ...

The AD8: A Brief Screening Tool for Very Mild Dementia

Jim Galvin and colleagues at Washington University, St. Louis, Missouri, have developed a simple tool to discern very early dementia in routine clinical settings. The field overwhelmingly agrees that dementia should be detected as early as possible, yet ...

APP Family: Clues to Function in Health and AD

The amyloid precursor protein was first cloned in 1987. Twenty years and 4,000+ papers later, the function of APP is still shrouded in mystery, despite the overwhelming weight of evidence linking the precursor protein to Alzheimer disease. Is the field ...

Non-coding RNAs in Neurodegeneration

Peter T. Nelson led this Webinar from 12:00-1:30 p.m. (U.S. Eastern Time) on Friday, 26 October 2007. Transcript: Participants: Peter Nelson (University of Kentucky), Ben Albensi (St. Boniface Res Ctr/Univ of Manitoba), Laura Turner (Eisai London Research ...

AD in the Oldest Old—What Does Aβ Have to Do With It?

In a keynote lecture at the Human Amyloid Imaging conference, held 12-13 January 2012 in Miami, Florida, Claudia Kawas argued that the oldest old should receive more attention. Kawas leads the world’s largest study of people 90 and older. Listen to the ...

Latest γ-Secretase Substrate Involved in Synaptic Stability, Autism?

Over the years, γ-secretase has garnered intense interest from scientists and drug developers who have targeted the multimeric complex in an attempt to curb production of amyloid-β (Aβ), the peptide believed to underlie Alzheimer’s disease. Meanwhile, the ...

International Student Workshop on AD

What makes a good grant proposal in Alzheimer’s research? How to develop and present it? What are funders looking for? Students from all over the world learned the answers by working hands-on with established Alzheimer’s disease researchers at a workshop ...

Using ADNI Data—Online Training, Part 1

On 4 April 2013, the Alzheimer's Disease Neuroimaging Initiative biostatistics core held the first session of its two-part online training course on using ADNI data. Led by Danielle Harvey of the University of California, Davis, the session gave a ...

Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.

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