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Making a BioMark on Alzheimer Disease

Our thanks to Practical Neurology for granting permission to reprint the full text of a recent article (.pdf) by John Trojanowski. John Trojanowski, Les Shaw, and Anne Fagan led this live discussion on 1 June 2005. Readers are invited to submit additional ...

Fluid Business: Could “Liquid” Protein Herald Neurodegeneration?

Could the protein aggregates that cause neurodegeneration turn out to be the cellular equivalent of ice cubes? Scientists investigating how proteins naturally transition between gas-like solutions, condensed liquids, solidified gels, and insoluble fibrils ...

Webinar: O Blood-Based Biomarker, Where Art Thou?

Our Webinar on 17 June 2013 covered the latest research and future directions on blood-based biomarkers discussed at a recent Alzheimer’s Drug Discovery Foundation/Alzheimer’s Association conference. Sid O’Bryant, Texas Tech University, Lubbock; Samantha ...

Using ADNI Data—Online Training, Part 1

On 4 April 2013, the Alzheimer's Disease Neuroimaging Initiative biostatistics core held the first session of its two-part online training course on using ADNI data. Led by Danielle Harvey of the University of California, Davis, the session gave a ...

International Student Workshop on AD

What makes a good grant proposal in Alzheimer’s research? How to develop and present it? What are funders looking for? Students from all over the world learned the answers by working hands-on with established Alzheimer’s disease researchers at a workshop ...

Latest γ-Secretase Substrate Involved in Synaptic Stability, Autism?

Over the years, γ-secretase has garnered intense interest from scientists and drug developers who have targeted the multimeric complex in an attempt to curb production of amyloid-β (Aβ), the peptide believed to underlie Alzheimer’s disease. Meanwhile, the ...

Who Should Use the New Diagnostic Guidelines? The Debate Continues

Download a PDF of this Forum Discussion Ever since new criteria came out for a research diagnosis of prodromal/preclinical Alzheimer’s disease, plus criteria for a research and clinical diagnosis of the MCI and dementia stages of the disease, they have ...

Intraneuronal Aβ: Was It APP All Along?

On 16 June 2011, ARF held a Webinar with Eddie Lee, Todd Golde, Gunnar Gouras, Frank LaFerla, Virginia Lee, Lars Nilsson, and Robert Vassar to discuss this study’s implications for intraneuronal Aβ and its role in AD pathogenesis. The Guest Moderator was ...

Volunteers Help Scientists Explore Down’s, Alzheimer’s Nexus

Children born with Down’s syndrome can receive excellent healthcare at specialized clinics, but once they become adults, their care often falls to doctors who may be less qualified to deal with their specific needs. The new Down Syndrome Center for ...

Imaging in Alzheimer's Disease: The Current State of Affairs

Are you confused about the various forms of PET and MRI that are used to image the brain? Do you know which protocol is more suited to detecting plaques and which can measure brain activity? Are you concerned when you see images of shrinking brains? Do ...

Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.

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