Updated Diagnostic Criteria and Management of Lewy Body Dementia
Despite being arguably the second most common dementing disorder, dementia with Lewy bodies, aka
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Despite being arguably the second most common dementing disorder, dementia with Lewy bodies, aka
frontotemporal dementia genes TMEM106B and progranulin, which reached genome-wide significance or trended
outright dementia that follows the onset of Aβ pathology. Does only Homo sapiens get Alzheimer’s disease?
frontotemporal dementias are similar to prion diseases such as Creutzfeldt-Jakob and bovine spongiform
the clinical phase expressed as the symptoms of dementia. The Three Phases of AD. Complex interplay
Have you ever been jolted wide awake by—biostatistics? That’s what happened on the last morning of the Clinical Trials on Alzheimer’s Disease conference held November 5-7 in Barcelona, Spain. At 8 a.m., as sleepy CTADeers slowly shuffled in, Suzanne Hendr
already have hints that the ALS- and frontotemporal dementia-linked protein TDP-43 makes liquid drops. Tau
in people with dementia, particularly those who also have cardiovascular disease (see van de Haar et
TREM2 in the CSF of patients with Alzheimer’s and frontotemporal dementia. The mutations weakened
between Aβ and cell-surface receptors in the neurovascular niche, and Nedergaard has defined a lymph-like
Wnt signaling pathway in frontotemporal dementia (see ARF related news story). Now, Schadt and
who do not have dementia yet. Traditional outcome measures were designed for moderate AD, and do not
underpinning for the environmental enrichment phenomenon. They suggest therapeutic possibilities while raising
Considering the overlap between neuropathological hallmarks and the development of dementia in late-onset
various neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementias, and
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