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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
ALZT-OP1 Cromolyn sodium, Intal,
Ibuprofen
Alzheimer's Disease (Phase 3) AZTherapies, Inc. Amyloid-Related, Inflammation Combination, Small Molecule
AMX0035 Amyotrophic Lateral Sclerosis (Phase 2), Alzheimer's Disease (Phase 2) Amylyx Pharmaceuticals Inc Other Combination, Small Molecule
AVP-786 Alzheimer's Disease (Phase 3), Schizophrenia (Phase 2) Avanir Pharmaceuticals, Concert Pharmaceuticals, Inc., Otsuka Pharmaceutical Co., Ltd. Other Neurotransmitters Combination, Small Molecule
AVP-923 Nuedexta,
Zenvia
Alzheimer's Disease (Phase 4), Amyotrophic Lateral Sclerosis (Phase 3), Parkinson's Disease (Phase 3) Avanir Pharmaceuticals, Otsuka Pharmaceutical Co., Ltd. Other Neurotransmitters Combination, Small Molecule
AXS-05 Dextromethorphan/bupropion Alzheimer's Disease (Phase 2/3) Axsome Therapeutics, Inc. Other Neurotransmitters Combination, Small Molecule
GENUS Gamma entrainment using sensory stimuli Alzheimer's Disease (Phase 1) Cognito Therapeutics, Inc. Amyloid-Related, Inflammation, Other Combination, Procedural Intervention
Gamunex Intravenous Immunoglobulin,
Human Albumin Combined With Flebogamma
Alzheimer's Disease (Phase 2/3) Grifols Biologicals Inc. Amyloid-Related, Inflammation Combination, Immunotherapy (passive) Immunodeficiency, chronic inflammatory demyelinating neuropathy
PXT864 PXT00864 Alzheimer's Disease (Phase 2) Pharnext Other Neurotransmitters Combination, Small Molecule