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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AAB-003 PF-05236812 Alzheimer's Disease (Discontinued) Janssen, Pfizer Amyloid-Related Immunotherapy (passive)
ABBV-0805 BAN0805 Parkinson's Disease (Phase 1) AbbVie, BioArctic AB alpha-synuclein Immunotherapy (passive)
ABBV-8E12 C2N 8E12 Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Phase 2) AbbVie, C2N Diagnostics, LLC Tau Immunotherapy (passive)
AL001 Frontotemporal Dementia (Phase 2) Alector Other Immunotherapy (passive)
AL002 Alzheimer's Disease (Phase 1) AbbVie, Alector Inflammation Immunotherapy (passive)
Aducanumab BIIB037 Alzheimer's Disease (Phase 3) Biogen, Neurimmune Amyloid-Related Immunotherapy (passive)
BAN2401 mAb158 Alzheimer's Disease (Phase 3) Biogen, Eisai Co., Ltd. Amyloid-Related Immunotherapy (passive)
BIIB076 NI-105,
6C5 huIgG1/l
Alzheimer's Disease (Phase 1) Biogen, Neurimmune Tau Immunotherapy (passive)
Bapineuzumab AAB-001 Alzheimer's Disease (Discontinued) Janssen, Pfizer Amyloid-Related Immunotherapy (passive)
Cinpanemab BIIB054,
NI-202
Parkinson's Disease (Phase 2) Biogen, Neurimmune alpha-synuclein Immunotherapy (passive)
Crenezumab MABT5102A ,
RG7412
Alzheimer's Disease (Phase 2) AC Immune SA, Genentech, Hoffmann-La Roche Amyloid-Related Immunotherapy (passive) None
Donanemab N3pG-Aβ Monoclonal Antibody,
LY3002813
Alzheimer's Disease (Phase 2) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive)
Etanercept Enbrel™ Alzheimer's Disease (Phase 2) Amgen, Inc., Pfizer Inflammation Immunotherapy (passive) Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondilysis
GSK933776 Alzheimer's Disease (Inactive) GlaxoSmithKline (GSK) Amyloid-Related Immunotherapy (passive)
Gammagard® Intravenous Immunoglobulin,
IVIg
Alzheimer's Disease (Discontinued) Baxter Healthcare Amyloid-Related, Inflammation Immunotherapy (passive) Immunodeficiency conditions
Gamunex Intravenous Immunoglobulin,
Human Albumin Combined With Flebogamma
Alzheimer's Disease (Phase 2/3) Grifols Biologicals Inc. Amyloid-Related, Inflammation Combination, Immunotherapy (passive) Immunodeficiency, chronic inflammatory demyelinating neuropathy
Gantenerumab RO4909832,
RG1450
Alzheimer's Disease (Phase 3) Chugai Pharmaceutical Co., Ltd., Hoffmann-La Roche Amyloid-Related Immunotherapy (passive)
Gosuranemab BIIB092,
BMS-986168, IPN007
Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Phase 2) Biogen, Bristol-Myers Squibb Tau Immunotherapy (passive)
JNJ-63733657 Mild AD (Phase 1) Janssen Tau Immunotherapy (passive)
LU AF82422 Parkinson's Disease (Phase 1) Genmab A/S, H. Lundbeck alpha-synuclein Immunotherapy (passive)
LY2599666 Alzheimer's Disease (Discontinued) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive)
LY3372993 Alzheimer's Disease (Phase 1) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive)
Lu AF87908 Alzheimer's Disease (Phase 1) H. Lundbeck Tau Immunotherapy (passive)
MEDI1341 TAK-341 Parkinson's Disease (Phase 1) AstraZeneca, Takeda Pharmaceutical Company alpha-synuclein Immunotherapy (passive)
MEDI1814 Alzheimer's Disease (Phase 1) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive)
Octagam®10% Intravenous Immunoglobulin,
NewGam
Alzheimer's Disease (Inactive), Mild Cognitive Impairment (Inactive) Octapharma Amyloid-Related, Inflammation Immunotherapy (passive) Immunodeficiency disorders
PNT001 Alzheimer's Disease (Phase 1), Traumatic Brain Injury (Phase 1) Pinteon Therapeutics Tau Immunotherapy (passive)
Ponezumab PF-04360365 Alzheimer's Disease (Discontinued), Cerebral Amyloid Angiopathy (Discontinued) Pfizer Amyloid-Related Immunotherapy (passive) None
Prasinezumab PRX002, RO7046015, RG7935, NEOD002 Parkinson's Disease (Phase 2) Hoffmann-La Roche, Prothena alpha-synuclein Immunotherapy (passive)
RG7345 RO6926496 Alzheimer's Disease (Discontinued) Tau Immunotherapy (passive)
RO7126209 RG6102,
Brain shuttle gantenerumab
Alzheimer's Disease (Phase 1) Hoffmann-La Roche Amyloid-Related Immunotherapy (passive)
SAR228810 Alzheimer's Disease (Phase 1) Sanofi Amyloid-Related Immunotherapy (passive)
Semorinemab RO7105705, MTAU9937A,
RG6100
Alzheimer's Disease (Phase 2) AC Immune SA, Genentech, Hoffmann-La Roche Tau Immunotherapy (passive)
Solanezumab LY2062430 Alzheimer's Disease (Phase 3) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive) None
UCB0107 UCB 0107 Progressive Supranuclear Palsy (Phase 1), Alzheimer's Disease (Phase 1) UCB S.A. Tau Immunotherapy (passive)
Zagotenemab LY3303560 Alzheimer's Disease (Phase 2) Eli Lilly & Co. Tau, Unknown Immunotherapy (passive)