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Name Synonyms FDA Status Company Target Type Therapy Type Approved
AL002 Alzheimer's Disease (Phase 1) AbbVie, Alector Inflammation Immunotherapy (active)
AL003 Alzheimer's Disease (Phase 1) AbbVie, Alector Inflammation Immunotherapy (active)
ALZT-OP1 Cromolyn sodium, Intal,
Alzheimer's Disease (Phase 3) AZTherapies, Inc. Amyloid-Related, Inflammation Small Molecule
Azeliragon PF-04494700 ,
Alzheimer's Disease (Inactive) Pfizer, TransTech Pharma, Inc., vTv Therapeutics LLC Amyloid-Related, Inflammation Small Molecule
CHF 5074 Mild Cognitive Impairment (Phase 2), Alzheimer's Disease (Inactive) CereSpir™ Incorporated, Chiesi Pharmaceuticals Inc. Amyloid-Related, Inflammation, Other Small Molecule
Celecoxib Celebrex Alzheimer's Disease (Discontinued) Pfizer Inflammation Small Molecule Pain, Arthritis
DNL747 SAR 443060 Alzheimer's Disease (Phase 1), Amyotrophic Lateral Sclerosis (Phase 1) Denali Therapeutics Inc., Sanofi Inflammation Small Molecule
Epigallocatechin Gallate (EGCG) Sunphenon EGCg Alzheimer's Disease (Phase 2/3), Down's Syndrome (Phase 2), Multiple System Atrophy (Phase 3) Taiyo International Amyloid-Related, Inflammation, Other Dietary Supplement
Etanercept Enbrel™ Alzheimer's Disease (Phase 2) Amgen, Inc., Pfizer Inflammation Immunotherapy (passive) Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondilysis
GC 021109 Alzheimer's Disease (Phase 1) GliaCure Inflammation Small Molecule
GENUS Gamma entrainment using sensory stimuli Alzheimer's Disease (Phase 1) Cognito Therapeutics, Inc. Amyloid-Related, Inflammation, Other Procedural Intervention
GM-CSF Leukine Sargramostim,
Alzheimer's Disease (Phase 2) Genzyme, Sanofi Inflammation, Other, Unknown Other Bone Marrow Stimulation
GRF6019 Alzheimer's Disease (Phase 2) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other
Gammagard® Intravenous Immunoglobulin,
Alzheimer's Disease (Discontinued) Baxter Healthcare Amyloid-Related, Inflammation Immunotherapy (passive) Immunodeficiency conditions
Gamunex Intravenous Immunoglobulin,
Human Albumin Combined With Flebogamma
Alzheimer's Disease (Phase 2/3) Grifols Biologicals Inc. Amyloid-Related, Inflammation Immunotherapy (passive) Immunodeficiency, chronic inflammatory demyelinating neuropathy
HF0220 Alzheimer's Disease (Discontinued) Newron Inflammation Small Molecule
Ibuprofen Advil™,
Nuprin™ ,
Alzheimer's Disease (Discontinued) Amyloid-Related, Inflammation Small Molecule Pain and Fever
Lornoxicam Alzheimer's Disease (Discontinued), Mild Cognitive Impairment (Discontinued) JSW Lifesciences Inflammation Small Molecule Pain in US
Minocycline Solodyn,
Alzheimer's Disease (Phase 2) Inflammation Small Molecule
Naproxen Aleve™,
Alzheimer's Disease (Discontinued) Procter & Gamble Inflammation Small Molecule Over-the-counter drug for reduction of pain, fever, inflammation, and stiffness.
Neflamapimod VX-745 Alzheimer's Disease (Phase 2) EIP Pharma, LLC Inflammation Small Molecule
Octagam®10% Intravenous Immunoglobulin,
Alzheimer's Disease (Inactive), Mild Cognitive Impairment (Inactive) Octapharma Amyloid-Related, Inflammation Immunotherapy (passive) Immunodeficiency disorders
PQ912 Alzheimer's Disease (Phase 2) Probiodrug AG Amyloid-Related, Inflammation Small Molecule
Pioglitazone AD4833,
Mild Cognitive Impairment (Phase 3) Takeda Pharmaceutical Company, Zinfandel Pharmaceuticals Inc. Inflammation, Other Small Molecule Type 2 diabetes mellitus
Prednisone Alzheimer's Disease (Discontinued) Inflammation Small Molecule
Rofecoxib Vioxx™ Alzheimer's Disease (Discontinued) Merck Inflammation Small Molecule Withdrawn from market
Thalidomide Thalomid® Alzheimer's Disease (Phase 2/3) Celgene Corporation Amyloid-Related, Inflammation Small Molecule
XPro1595 INB03, NeuLiv, XENP1595, DN-TNF, XENP345 Alzheimer's Disease (Phase 1) INmune Bio Inc. Inflammation Other
Young Plasma Progressive Supranuclear Palsy (Phase 1), Alzheimer's Disease (Phase 1) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other