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Name Synonyms FDA Status Company Target Type Therapy Type Approved
AXS-05 Dextromethorphan/bupropion Alzheimer's Disease (Phase 2/3) Axsome Therapeutics, Inc. Other Neurotransmitters Combination, Small Molecule
Atuzaginstat COR388 Alzheimer's Disease (Phase 2/3) Cortexyme, Inc. Other Small Molecule
Blarcamesine Anavex 2-73 Alzheimer's Disease (Phase 2/3), Parkinson's Disease Dementia (Phase 2), Parkinson's Disease (Phase 1) Anavex Life Science Corp. Other Small Molecule
Metformin Glucophage,
Glucophage XR
Alzheimer's Disease (Phase 2/3) Other Small Molecule Type 2 Diabetes
Thalidomide Thalomid® Alzheimer's Disease (Phase 2/3) Celgene Corporation Amyloid-Related, Inflammation Small Molecule
Vascepa Icosapent ethyl (IPE),
Ethyl eicosapentaenoic acid (E-EPA),
Alzheimer's Disease (Phase 2/3) Other Small Molecule Severe hypertriglyceridemia, and to lower risk of cardiovascular events in people with elevated triglycerides