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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AXS-05 Dextromethorphan/bupropion Alzheimer's Disease (Phase 2/3) Axsome Therapeutics, Inc. Other Neurotransmitters Combination, Small Molecule
Azeliragon PF-04494700,
TTP488
Alzheimer's Disease (Phase 2/3) Pfizer, TransTech Pharma, Inc., vTv Therapeutics LLC Amyloid-Related, Inflammation Small Molecule
Metformin Glucophage,
Glucophage XR
Alzheimer's Disease (Phase 2/3) Other Small Molecule Type 2 Diabetes
Thalidomide Thalomid® Alzheimer's Disease (Phase 2/3) Celgene Corporation Amyloid-Related, Inflammation Small Molecule
Umibecestat CNP520,
BACE Inhibitor
Alzheimer's Disease (Phase 2/3) Amgen, Inc., Novartis Pharmaceuticals Corporation Amyloid-Related Small Molecule
Vascepa Icosapent ethyl (IPE),
Ethyl eicosapentaenoic acid (E-EPA),
AMR101,
Miraxion
Alzheimer's Disease (Phase 2/3) Other Small Molecule Severe hypertriglyceridemia, and to lower risk of cardiovascular events in people with elevated triglycerides