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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AZD3480 ispronicline,
TC-1734
Alzheimer's Disease (Inactive) AstraZeneca, Targacept Cholinergic System Small Molecule
Atorvastatin Lipitor™ ,
Zarator®,
Sortis®,
Tahor®
Alzheimer's Disease (Inactive) Pfizer Cholesterol Small Molecule Hypercholesterolaemia
CHF 5074 Mild Cognitive Impairment (Phase 2), Alzheimer's Disease (Inactive) CereSpir™ Incorporated, Chiesi Pharmaceuticals Inc. Amyloid-Related, Inflammation, Other Small Molecule
DNL747 SAR 443060 Alzheimer's Disease (Inactive), Amyotrophic Lateral Sclerosis (Inactive) Denali Therapeutics Inc., Sanofi Inflammation Small Molecule
Dapsone Avlosulfon,
Diaminodiphenylsulfone,
DDS
Alzheimer's Disease (Inactive) Immune Network Ltd. Other Small Molecule Leprosy, malaria, some bacterial skin infections
ELND005 AZD-103,
Scyllo-inositol,
cyclohexane-1,2,3,4,5,6-hexol
Alzheimer's Disease (Inactive) Elan Corporation, Opko Health, Speranza Therapeutics, Transition Therapeutics, Inc. Amyloid-Related Small Molecule None
Edonerpic T-817 MA, T 817 Alzheimer's Disease (Inactive) Toyama Chemical Co., Ltd. Other, Unknown Small Molecule
Exendin-4 Exenatide,
Byetta,
Bydureon
Alzheimer's Disease (Inactive), Parkinson's Disease (Phase 3) Other Small Molecule Diabetes mellitus in US
Huperzine A ZT-1,
DEBIO 9902 ,
Qian ceng ta,
Cerebra capsule,
Pharmassure Memorall capsule
Alzheimer's Disease (Inactive) Debiopharm Group™, Neuro-Hitech, Inc. Cholinergic System Small Molecule, Supplement, Dietary None
MKC-231 Alzheimer's Disease (Inactive) Mitsubishi Tanabe Pharma Unknown Small Molecule None
NGX267 AF267B Alzheimer's Disease (Inactive) TorreyPines Therapeutics, Inc. Cholinergic System Small Molecule None
Nilvadipine Nilvad,
Nivadil,
ARC029
Alzheimer's Disease (Inactive) Archer Pharmaceuticals, Inc. Other Small Molecule
PRX-03140 Potassium salt Alzheimer's Disease (Inactive) Epix Pharmaceuticals Other Small Molecule
Phenserine Alzheimer's Disease (Inactive) Annovis Bio, TorreyPines Therapeutics, Inc. Cholinergic System Small Molecule
RG3487 RO5313534,
MEM 3454
Alzheimer's Disease (Inactive) Roche Cholinergic System Small Molecule
ST101 ZSET1446 Alzheimer's Disease (Inactive) Sonexa Therapeutics, Inc. Unknown Small Molecule
Sabeluzole R58735 Alzheimer's Disease (Inactive) Unknown Small Molecule
TPI 287 Alzheimer's Disease (Inactive), Corticobasal Degeneration (Inactive), Progressive Supranuclear Palsy (Phase 1) Cortice Biosciences Tau Small Molecule
Valproate Depakote,
Depakene,
Valproic acid ,
Divalproex sodium
Alzheimer's Disease (Inactive) Abbott Laboratories Other Neurotransmitters Small Molecule Epilepsy, Bipolar disorder, Migraine